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    CD38 CD38 molecule [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009409, updated on 8-Mar-2024

    Summary

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    Gene symbol
    CD38
    Gene description
    CD38 molecule
    See related
    Ensembl:ENSOCUG00000017793
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    ADPRC 1
    Orthologs
    human mouse all
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    Genomic context

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    See CD38 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 2 NC_067375.1 (6840850..6893821)

    Chromosome 2 - NC_067375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127486370 Neighboring gene bone marrow stromal cell antigen 1 Neighboring gene tripartite motif-containing protein 5-like Neighboring gene fibroblast growth factor-binding protein 1 Neighboring gene fibroblast growth factor-binding protein 1 Neighboring gene fibroblast growth factor-binding protein 1 Neighboring gene fibroblast growth factor-binding protein 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_067375.1 Chromosome 2 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, expression, and functional characterization of a novel member of the CD38 family of ADP-ribosyl cyclases. Adebanjo OA, et al. Biochem Biophys Res Commun, 2000 Jul 14. PMID 10891341
    2. Synthesis of the Ca(2+)-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling. Lin WK, et al. J Biol Chem, 2017 Aug 11. PMID 28539361, Free PMC Article
    3. CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption. Sun L, et al. J Cell Biol, 1999 Sep 6. PMID 10477767, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+ nucleosidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphorus-oxygen lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of B cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
    Names
    2'-phospho-ADP-ribosyl cyclase
    2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
    2'-phospho-cyclic-ADP-ribose transferase
    ADP-ribosyl cyclase 1
    CD38/ADP-ribosyl cyclase
    cADPr hydrolase 1
    cyclic ADP-ribose hydrolase 1
    NP_001076152.1
    XP_008272264.1
    XP_051684802.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082683.1 → NP_001076152.1  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

      See identical proteins and their annotated locations for NP_001076152.1

      Status: PROVISIONAL

      Source sequence(s)
      AF272974
      UniProtKB/Swiss-Prot
      Q9MZ03
      Related
      ENSOCUP00000015283.2, ENSOCUT00000017793.4
      Conserved Domains (1) summary
      pfam02267
      Location:53 → 282
      Rib_hydrolayse; ADP-ribosyl cyclase

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067375.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      6840850..6893821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008274042.3 → XP_008272264.1  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 isoform X1

      See identical proteins and their annotated locations for XP_008272264.1

      UniProtKB/TrEMBL
      G1TEG2
      Conserved Domains (1) summary
      pfam02267
      Location:53 → 282
      Rib_hydrolayse; ADP-ribosyl cyclase

    2. XM_051828842.1 → XP_051684802.1  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 isoform X1

      UniProtKB/TrEMBL
      G1TEG2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MZ03.1 GenPept UniProtKB/Swiss-Prot:Q9MZ03

    Gene LinkOut

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