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    L large polymerase protein [ Measles morbillivirus ]

    Gene ID: 1489802, updated on 18-Aug-2023

    Summary

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    Gene symbol
    L
    Gene description
    large polymerase protein
    Locus tag
    MeVgp6
    Gene type
    protein coding
    RNA name
    L gene
    RefSeq status
    PROVISIONAL
    Organism
    Measles morbillivirus (strain: Ichinose-B95a)
    Lineage
    Viruses; ssRNA viruses; ssRNA negative-strand viruses; Mononegavirales; Paramyxoviridae; Morbillivirus
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    Genomic context

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    Sequence:
    NC_001498.1 (9212..15854)

    NC_001498.1Genomic Context describing neighboring genes Neighboring gene fusion protein Neighboring gene hemagglutinin protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001498.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The phosphoprotein (P) and L binding sites reside in the N-terminus of the L subunit of the measles virus RNA polymerase. Cevik B, et al. Virology, 2004 Oct 1. PMID 15351217
    2. The measles virus nucleocapsid protein tail domain is dispensable for viral polymerase recruitment and activity. Krumm SA, et al. J Biol Chem, 2013 Oct 11. PMID 24003217, Free PMC Article
    3. The measles virus replication cycle. Rima BK, et al. Curr Top Microbiol Immunol, 2009. PMID 19198563
    4. Comparative nucleotide sequence analyses of the entire genomes of B95a cell-isolated and vero cell-isolated measles viruses from the same patient. Takeuchi K, et al. Virus Genes, 2000. PMID 10949953

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that the viral RdRp polymerase complex is capable of productively docking directly to the nucleocapsid core.
      Title: The measles virus nucleocapsid protein tail domain is dispensable for viral polymerase recruitment and activity.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

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    Preferred Names
    large polymerase protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001498.1 Reference assembly

      Range
      9212..15854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_056924.1 large polymerase protein [Measles morbillivirus]

      See identical proteins and their annotated locations for NP_056924.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9WMB3
      UniProtKB/TrEMBL
      Q784S0, Q9WPZ1
      Conserved Domains (2) summary
      TIGR04198
      Location:1235 → 2180
      paramyx_RNAcap; mRNA capping enzyme, paramyxovirus family
      pfam00946
      Location:13 → 1118
      Mononeg_RNA_pol; Mononegavirales RNA dependent RNA polymerase
    Nucleotide Protein
    Heading Accession and Version

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