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    ca2 carbonic anhydrase [ Solanum lycopersicum (tomato) ]

    Gene ID: 543803, updated on 1-Nov-2024

    Summary

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    Gene symbol
    ca2
    Gene description
    carbonic anhydrase
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Solanum lycopersicum
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Solanum subgen. Lycopersicon
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    Genomic context

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    See ca2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_09 current SLM_r2.1 (GCF_036512215.1) 2 NC_090801.1 (65730182..65733909)
    103 previous assembly SL3.0 (GCF_000188115.4) 2 NC_015439.3 (50071765..50075360)

    Chromosome 2 - NC_090801.1Genomic Context describing neighboring genes Neighboring gene probable phospholipid-transporting ATPase 8 Neighboring gene uncharacterized LOC101250946 Neighboring gene protease Do-like 1, chloroplastic Neighboring gene protein KINESIN LIGHT CHAIN-RELATED 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expressed sequence tags from the laboratory-grown miniature tomato (Lycopersicon esculentum) cultivar Micro-Tom and mining for single nucleotide polymorphisms and insertions/deletions in tomato cultivars. Yamamoto N, et al. Gene, 2005 Aug 15. PMID 15975739
    2. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics. Aoki K, et al. BMC Genomics, 2010 Mar 30. PMID 20350329, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbon utilization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbonic anhydrase
    NP_001234048.1
    NP_001299833.1
    XP_069149241.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001247119.2 → NP_001234048.1  carbonic anhydrase isoform 1

      See identical proteins and their annotated locations for NP_001234048.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
      Source sequence(s)
      AEKE03003138, AJ849376
      UniProtKB/TrEMBL
      Q5NE20
      Conserved Domains (2) summary
      PLN03014
      Location:1 → 321
      PLN03014; carbonic anhydrase
      cl00391
      Location:65 → 320
      beta_CA; Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ...

    2. NM_001312904.1 → NP_001299833.1  carbonic anhydrase isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a longer protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      BP902638, DB693998, DB706868
      Conserved Domains (2) summary
      PLN03014
      Location:1 → 332
      PLN03014; carbonic anhydrase
      cl00391
      Location:65 → 320
      beta_CA; Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an ...

    RefSeqs of Annotated Genomes: GCF_036512215.1-RS_2024_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference SLM_r2.1 Primary Assembly

    Genomic

    1. NC_090801.1 Reference SLM_r2.1 Primary Assembly

      Range
      65730182..65733909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_069293140.1 → XP_069149241.1  carbonic anhydrase isoform X1

    Nucleotide Protein
    Heading Accession and Version

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