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    mt-nd3 NADH dehydrogenase 3, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 140533, updated on 26-Jun-2024

    Summary

    Official Symbol
    mt-nd3provided by ZNC
    Official Full Name
    NADH dehydrogenase 3, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-011205-9
    See related
    AllianceGenome:ZFIN:ZDB-GENE-011205-9
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    mtnd3; ND3
    Summary
    Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. Orthologous to human MT-ND3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) MT (non-nuclear) NC_002333.2 (10590..10940)
    105 previous assembly GRCz10 (GCF_000002035.5) MT (non-nuclear) NC_002333.2 (10590..10940)

    Chromosome MT - NC_002333.2Genomic Context describing neighboring genes Neighboring gene ATP synthase 8 Neighboring gene ATP synthase 6 Neighboring gene cytochrome c oxidase subunit III Neighboring gene tRNA-Gly Neighboring gene tRNA-Arg Neighboring gene NADH dehydrogenase subunit 4L Neighboring gene NADH dehydrogenase subunit 4 Neighboring gene tRNA-His Neighboring gene tRNA-Ser

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables NADH dehydrogenase (ubiquinone) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables NADH dehydrogenase (ubiquinone) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respirasome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002333.2 Reference assembly

      Range
      10590..10940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_059338.1 NADH dehydrogenase subunit 3 (mitochondrion) [Danio rerio]

      See identical proteins and their annotated locations for NP_059338.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MIY3
      Related
      ENSDARP00000087876.3
      Conserved Domains (1) summary
      MTH00136
      Location:1116
      ND3; NADH dehydrogenase subunit 3; Provisional