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    mt-atp6 ATP synthase 6, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 140519, updated on 27-Mar-2024

    Summary

    Official Symbol
    mt-atp6provided by ZNC
    Official Full Name
    ATP synthase 6, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-011205-18
    See related
    AllianceGenome:ZFIN:ZDB-GENE-011205-18
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    mtatp6; ATP6
    Summary
    Predicted to enable proton transmembrane transporter activity. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to act upstream of or within ATP biosynthetic process and ion transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; NARP syndrome; Parkinson's disease; multiple sclerosis; and systemic lupus erythematosus. Orthologous to human MT-ATP6 (mitochondrially encoded ATP synthase membrane subunit 6). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See mt-atp6 in Genome Data Viewer
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) MT (non-nuclear) NC_002333.2 (9052..9735)
    105 previous assembly GRCz10 (GCF_000002035.5) MT (non-nuclear) NC_002333.2 (9052..9735)

    Chromosome MT - NC_002333.2Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit II Neighboring gene tRNA-Lys Neighboring gene ATP synthase 8 Neighboring gene cytochrome c oxidase subunit III Neighboring gene tRNA-Gly Neighboring gene NADH dehydrogenase subunit 3 Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    • zgc:85637

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within ATP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proton motive force-driven ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of mitochondrial proton-transporting ATP synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ATP synthase 6
    Names
    ATP synthase F0 subunit 6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002333.2 Reference assembly

      Range
      9052..9735
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_059336.1 ATP synthase F0 subunit 6 (mitochondrion) [Danio rerio]

      See identical proteins and their annotated locations for NP_059336.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MIY5
      UniProtKB/TrEMBL
      A0A0A0VDB1
      Related
      ENSDARP00000087874.3
      Conserved Domains (1) summary
      MTH00132
      Location:1227
      ATP6; ATP synthase F0 subunit 6; Provisional