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    Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 93674, updated on 2-Nov-2024

    Summary

    Official Symbol
    Nat8f3provided by MGI
    Official Full Name
    N-acetyltransferase 8 (GCN5-related) family member 3provided by MGI
    Primary source
    MGI:MGI:2136449
    See related
    Ensembl:ENSMUSG00000051262 AllianceGenome:MGI:2136449
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cml3; 4833414A14Rik; 4930583K21Rik
    Summary
    Enables histone H4 acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within axis elongation and negative regulation of cell adhesion. Located in nuclear membrane. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)) and NAT8B (N-acetyltransferase 8B (putative, gene/pseudogene)). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in kidney adult (RPKM 106.4) and bladder adult (RPKM 4.7) See more
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    Genomic context

    See Nat8f3 in Genome Data Viewer
    Location:
    6 C3; 6 37.48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (85737613..85742726, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (85760631..85765767, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ALMS1, centrosome and basal body associated Neighboring gene STARR-seq mESC enhancer starr_16506 Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 7 Neighboring gene ALMS1, centrosome and basal body associated, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_16507 Neighboring gene ALMS1, centrosome and basal body associated, pseudogene 2 Neighboring gene microRNA 6375

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within axis elongation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in gastrulation with mouth forming second NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of cell adhesion ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in endoplasmic reticulum ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in extracellular space ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-acetyltransferase family 8 member 3
    Names
    N-acetyltransferase CML3
    camello-like 3
    camello-like protein 3
    probable N-acetyltransferase CML3
    NP_001032931.1
    XP_017177330.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037842.3NP_001032931.1  N-acetyltransferase family 8 member 3

      See identical proteins and their annotated locations for NP_001032931.1

      Status: VALIDATED

      Source sequence(s)
      AC162313, AK046314
      Consensus CDS
      CCDS20299.1
      UniProtKB/TrEMBL
      A0A0R4J157
      Related
      ENSMUSP00000093431.5, ENSMUST00000050780.8
      Conserved Domains (1) summary
      pfam13508
      Location:106195
      Acetyltransf_7; Acetyltransferase (GNAT) domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      85737613..85742726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321841.2XP_017177330.1  N-acetyltransferase family 8 member 3 isoform X1

      UniProtKB/TrEMBL
      A0A0R4J157
      Related
      ENSMUSP00000131413.2, ENSMUST00000168531.2
      Conserved Domains (1) summary
      pfam13508
      Location:106195
      Acetyltransf_7; Acetyltransferase (GNAT) domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_053097.2: Suppressed sequence

      Description
      NM_053097.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.