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    SSADH succinic semialdehyde dehydrogenase [ Solanum lycopersicum (tomato) ]

    Gene ID: 100147726, updated on 1-Nov-2024

    Summary

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    Gene symbol
    SSADH
    Gene description
    succinic semialdehyde dehydrogenase
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Solanum lycopersicum
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Solanum subgen. Lycopersicon
    Also known as
    LeSSADH
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    Genomic context

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    See SSADH in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_09 current SLM_r2.1 (GCF_036512215.1) 9 NC_090808.1 (67618248..67620833, complement)
    103 previous assembly SL3.0 (GCF_000188115.4) 9 NC_015446.3 (70618672..70621257, complement)

    Chromosome 9 - NC_090808.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104649400 Neighboring gene uncharacterized LOC101264371 Neighboring gene uncharacterized LOC101264673 Neighboring gene 26S proteasome non-ATPase regulatory subunit 13 homolog B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics. Aoki K, et al. BMC Genomics, 2010 Mar 30. PMID 20350329, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables succinate-semialdehyde dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    succinic semialdehyde dehydrogenase
    NP_001233841.1
    NP_001293103.1
    NP_001293104.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001246912.3 → NP_001233841.1  succinic semialdehyde dehydrogenase isoform a

      See identical proteins and their annotated locations for NP_001233841.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AEKE03003145
      UniProtKB/TrEMBL
      B1Q3F8
      Conserved Domains (1) summary
      PLN02278
      Location:28 → 522
      PLN02278; succinic semialdehyde dehydrogenase

    2. NM_001306174.1 → NP_001293103.1  succinic semialdehyde dehydrogenase isoform a

      See identical proteins and their annotated locations for NP_001293103.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AEKE03003145
      UniProtKB/TrEMBL
      B1Q3F8
      Conserved Domains (1) summary
      PLN02278
      Location:28 → 522
      PLN02278; succinic semialdehyde dehydrogenase

    3. NM_001306175.1 → NP_001293104.1  succinic semialdehyde dehydrogenase isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site at the beginning of the second exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AEKE03003145
      Conserved Domains (1) summary
      PLN02278
      Location:1 → 493
      PLN02278; succinic semialdehyde dehydrogenase

    RefSeqs of Annotated Genomes: GCF_036512215.1-RS_2024_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference SLM_r2.1 Primary Assembly

    Genomic

    1. NC_090808.1 Reference SLM_r2.1 Primary Assembly

      Range
      67618248..67620833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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