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    His2A:CG33808 histone H2A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772282, updated on 2-Nov-2024

    Summary

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    Official Symbol
    His2A:CG33808provided by FlyBase
    Official Full Name
    histone H2Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053808
    Locus tag
    Dmel_CG33808
    See related
    AllianceGenome:FB:FBgn0053808
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33808; Dmel\CG33808
    Summary
    Predicted to enable DNA binding activity. Involved in larval somatic muscle development. Located in nucleus and polytene chromosome band. Orthologous to several human genes including H2AC11 (H2A clustered histone 11); H2AC12 (H2A clustered histone 12); and H2AC13 (H2A clustered histone 13). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See His2A:CG33808 in Genome Data Viewer
    Location:
    39D3-39D3; 2-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21433862..21434337)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21433862..21434337)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H1 Neighboring gene histone H2B Neighboring gene small non-coding RNA 430b Neighboring gene histone H4 Neighboring gene histone H3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. tRNA derived insertion element in histone gene repeating unit of Drosophila melanogaster. Matsuo Y, et al. Nucleic Acids Res, 1989 Jan 11. PMID 2536150, Free PMC Article
    2. Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster. Leach TJ, et al. J Biol Chem, 2000 Jul 28. PMID 10801889
    3. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    4. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in larval somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleosome assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nucleosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of nucleosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of nucleosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H2A
    Names
    CG33808-PA
    His2A:CG33808-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      21433862..21434337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032121.2 → NP_001027292.1  histone H2A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027292.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P84051, Q4ABC7
      Conserved Domains (1) summary
      PTZ00017
      Location:16 → 124
      PTZ00017; histone H2A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P84051.2 P84051

    Gene LinkOut

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