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    Sorbs1 sorbin and SH3 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 20411, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Sorbs1provided by MGI
    Official Full Name
    sorbin and SH3 domain containing 1provided by MGI
    Primary source
    MGI:MGI:700014
    See related
    Ensembl:ENSMUSG00000025006 AllianceGenome:MGI:700014
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CAP; Sh3d5; SH3P12; mKIAA1296; 2310065E01Rik; 9530001P15Rik
    Summary
    Enables enzyme binding activity; insulin receptor binding activity; and signaling receptor complex adaptor activity. Involved in several processes, including focal adhesion assembly; insulin receptor signaling pathway; and positive regulation of biosynthetic process. Acts upstream of or within acetylcholine receptor signaling pathway and regulation of skeletal muscle acetylcholine-gated channel clustering. Located in several cellular components, including adherens junction; nuclear matrix; and stress fiber. Part of flotillin complex. Is expressed in several structures, including 1st branchial arch mandibular component; alimentary system; central nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human SORBS1 (sorbin and SH3 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in bladder adult (RPKM 34.6), subcutaneous fat pad adult (RPKM 30.5) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sorbs1 in Genome Data Viewer
    Location:
    19 C3; 19 34.25 cM
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (40280484..40502399, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (40292040..40513955, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46132 Neighboring gene RIKEN cDNA A930028N01 gene Neighboring gene predicted gene, 41845 Neighboring gene predicted gene 5693 Neighboring gene STARR-seq mESC enhancer starr_46134 Neighboring gene STARR-positive B cell enhancer mm9_chr19:40582986-40583287 Neighboring gene STARR-positive B cell enhancer ABC_E8749 Neighboring gene aldehyde dehydrogenase 18 family, member A1 Neighboring gene protein tyrosine phosphatase 4a1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E11675 Neighboring gene STARR-positive B cell enhancer ABC_E7650 Neighboring gene predicted gene, 27042

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. cDNA cloning and functional characterization of a novel splice variant of c-Cbl-associated protein from mouse skeletal muscle. Alcazar O, et al. Biochem Biophys Res Commun, 2004 Apr 23. PMID 15047181
    2. [Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance]. Li D, et al. Zhong Xi Yi Jie He Xue Bao, 2012 Aug. PMID 22883405
    3. The adapter protein c-Cbl-associated protein (CAP) protects from acute CVB3-mediated myocarditis through stabilization of type I interferon production and reduced cytotoxicity. Valaperti A, et al. Basic Res Cardiol, 2014 May. PMID 24763933
    4. CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells. Aye CC, et al. Int J Mol Sci, 2023 Feb 8. PMID 36834818, Free PMC Article
    5. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Lesniewski LA, et al. Nat Med, 2007 Apr. PMID 17351624

    See all (80) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells.
      Title: CBL/CAP Is Essential for Mitochondria Respiration Complex I Assembly and Bioenergetics Efficiency in Muscle Cells.
    2. These observations reveal a critical role of vinexin alpha and CAP in mechanotransduction and MSC differentiation.
      Title: Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells.
    3. The first SNP rs29972765 is located in a gene desert on chromosome 18, about 72 kb upstream of Skor2 . The second SNP rs30415957 resides in the intron of Plce1.The remaining two SNPs (rs30768258 and rs31216810) are close to each other on chromosome 19, in the vicinity of Sorbs1. Knockdown of Sorbs1 by siRNA attenuates the induction of differentiation marker gene Prl8a2
      Title: Genome-Wide Association Mapping for Female Infertility in Inbred Mice.
    4. The study screened CrkL binding proteins using RNA interference (RNAi) and identified Sorbs1 and Sorbs2 as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.
      Title: Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation.
    5. Suggest a novel modulatory role for CAP in the heart as a key protein stabilizing antiviral type I interferon production, while protecting from excessive cytotoxic responses in CVB3 mediated endocarditis.
      Title: The adapter protein c-Cbl-associated protein (CAP) protects from acute CVB3-mediated myocarditis through stabilization of type I interferon production and reduced cytotoxicity.
    6. Low- and high-dose ursolic acid can improve the glycometabolism and differentiation of 3T3-L1 adipocytes with insulin resistance by up-regulating the expression of CAP.
      Title: [Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance].
    7. a novel signaling network containing FRS2, CAP and flotillin-1
      Title: Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2.
    8. The novel ponsin isoform and its interaction with Nck1/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation.
      Title: Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells.
    9. CAP provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity
      Title: Identification of CAP as a costameric protein that interacts with filamin C.
    10. Bone marrow-specific Sorbs1 (Cap) gene deletion protects against high-fat diet-induced insulin resistance.
      Title: Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables insulin receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables insulin receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within acetylcholine receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cell-substrate adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cellular response to insulin stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in focal adhesion assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in insulin receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of D-glucose import IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of D-glucose import IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of glycogen biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of insulin receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of skeletal muscle acetylcholine-gated channel clustering IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in stress fiber assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell-substrate junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell-substrate junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of flotillin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane raft IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in stress fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sorbin and SH3 domain-containing protein 1
    Names
    SH3 domain protein 5
    c-Cbl-associated protein
    ponsin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034962.1 → NP_001030134.1  sorbin and SH3 domain-containing protein 1 isoform 3

      See identical proteins and their annotated locations for NP_001030134.1

      Status: VALIDATED

      Source sequence(s)
      AC144949, AF078667, AK035212, AK087553, BY031726
      Consensus CDS
      CCDS37981.1
      UniProtKB/TrEMBL
      E9Q6A3
      Related
      ENSMUSP00000153336.2, ENSMUST00000225786.2
      Conserved Domains (5) summary
      smart00459
      Location:233 → 279
      Sorb; Sorbin homologous domain
      cd11916
      Location:655 → 713
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:476 → 530
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:550 → 607
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam06075
      Location:9 → 166
      DUF936; Plant protein of unknown function (DUF936)

    2. NM_001034963.1 → NP_001030135.1  sorbin and SH3 domain-containing protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001030135.1

      Status: VALIDATED

      Source sequence(s)
      AC144949, AF078666, AK035212, AK087553, AK122487, BY031726
      Consensus CDS
      CCDS37978.1
      UniProtKB/TrEMBL
      E9PYX6
      Related
      ENSMUSP00000126460.2, ENSMUST00000165212.8
      Conserved Domains (4) summary
      cd11916
      Location:665 → 723
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:486 → 540
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:560 → 617
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:196 → 237
      Sorb; Sorbin homologous domain

    3. NM_001034964.1 → NP_001030136.1  sorbin and SH3 domain-containing protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC144949, AF078667, AK035212, U58883
      Consensus CDS
      CCDS37979.1
      UniProtKB/TrEMBL
      E9QNA7
      Related
      ENSMUSP00000097065.4, ENSMUST00000099466.10
      Conserved Domains (4) summary
      cd11916
      Location:681 → 739
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:502 → 556
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:576 → 633
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam02208
      Location:206 → 247
      Sorb; Sorbin homologous domain

    4. NM_001403055.1 → NP_001389984.1  sorbin and SH3 domain-containing protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC142101, AC144949, AC170187

    5. NM_001403056.1 → NP_001389985.1  sorbin and SH3 domain-containing protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC142101, AC144949, AC170187
      UniProtKB/TrEMBL
      A0A286YCI8
      Related
      ENSMUSP00000153009.2, ENSMUST00000224667.2

    6. NM_009166.3 → NP_033192.2  sorbin and SH3 domain-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC142101, AC144949, AC170187
      Consensus CDS
      CCDS89388.1
      UniProtKB/TrEMBL
      A0A286YCQ0
      Related
      ENSMUSP00000152957.2, ENSMUST00000224247.2
      Conserved Domains (5) summary
      smart00459
      Location:203 → 249
      Sorb; Sorbin homologous domain
      cd11916
      Location:625 → 683
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:446 → 500
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:520 → 577
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam05109
      Location:16 → 219
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    7. NM_178362.1 → NP_848139.1  sorbin and SH3 domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC144949, AK087553
      Consensus CDS
      CCDS37980.1
      UniProtKB/TrEMBL
      D3Z5J3
      Related
      ENSMUSP00000153313.2, ENSMUST00000225153.2
      Conserved Domains (4) summary
      cd11916
      Location:879 → 937
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:700 → 754
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:774 → 831
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cl02617
      Location:330 → 368
      Sorb; Sorbin homologous domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      40280484..40502399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161485.1 → XP_036017378.1  sorbin and SH3 domain-containing protein 1 isoform X40

      Conserved Domains (4) summary
      smart00459
      Location:202 → 248
      Sorb; Sorbin homologous domain
      cd11916
      Location:624 → 682
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:445 → 499
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:519 → 576
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    2. XM_036161480.1 → XP_036017373.1  sorbin and SH3 domain-containing protein 1 isoform X22

      UniProtKB/Swiss-Prot
      Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9
      Conserved Domains (4) summary
      smart00459
      Location:202 → 248
      Sorb; Sorbin homologous domain
      cd11916
      Location:1113 → 1171
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:934 → 988
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1008 → 1065
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    3. XM_030250821.1 → XP_030106681.1  sorbin and SH3 domain-containing protein 1 isoform X32

      Conserved Domains (4) summary
      smart00459
      Location:202 → 248
      Sorb; Sorbin homologous domain
      cd11916
      Location:714 → 772
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:535 → 589
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:609 → 666
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    4. XM_030250804.1 → XP_030106664.1  sorbin and SH3 domain-containing protein 1 isoform X11

      Conserved Domains (4) summary
      smart00459
      Location:202 → 248
      Sorb; Sorbin homologous domain
      cd11916
      Location:1568 → 1626
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1074 → 1128
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1148 → 1205
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    5. XM_036161478.1 → XP_036017371.1  sorbin and SH3 domain-containing protein 1 isoform X17

      UniProtKB/Swiss-Prot
      Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9
      Conserved Domains (4) summary
      smart00459
      Location:212 → 258
      Sorb; Sorbin homologous domain
      cd11916
      Location:1157 → 1215
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:978 → 1032
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1052 → 1109
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    6. XM_036161475.1 → XP_036017368.1  sorbin and SH3 domain-containing protein 1 isoform X10

      Conserved Domains (4) summary
      smart00459
      Location:212 → 258
      Sorb; Sorbin homologous domain
      cd11916
      Location:1578 → 1636
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1084 → 1138
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1158 → 1215
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    7. XM_017318090.2 → XP_017173579.1  sorbin and SH3 domain-containing protein 1 isoform X9

      Conserved Domains (4) summary
      smart00459
      Location:223 → 269
      Sorb; Sorbin homologous domain
      cd11916
      Location:1589 → 1647
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1095 → 1149
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1169 → 1226
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    8. XM_030250827.2 → XP_030106687.1  sorbin and SH3 domain-containing protein 1 isoform X41

      Conserved Domains (4) summary
      smart00459
      Location:193 → 239
      Sorb; Sorbin homologous domain
      cd11916
      Location:615 → 673
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:436 → 490
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:510 → 567
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    9. XM_017318096.3 → XP_017173585.1  sorbin and SH3 domain-containing protein 1 isoform X37

      Conserved Domains (4) summary
      smart00459
      Location:193 → 239
      Sorb; Sorbin homologous domain
      cd11916
      Location:643 → 701
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:464 → 518
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:538 → 595
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    10. XM_017318097.3 → XP_017173586.1  sorbin and SH3 domain-containing protein 1 isoform X39

      UniProtKB/TrEMBL
      A0A286YCQ0
      Related
      ENSMUSP00000153097.2, ENSMUST00000225148.2
      Conserved Domains (5) summary
      smart00459
      Location:203 → 249
      Sorb; Sorbin homologous domain
      cd11916
      Location:625 → 683
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:446 → 500
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:520 → 577
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam05109
      Location:16 → 219
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    11. XM_036161479.1 → XP_036017372.1  sorbin and SH3 domain-containing protein 1 isoform X21

      UniProtKB/Swiss-Prot
      Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9
      Conserved Domains (4) summary
      smart00459
      Location:203 → 249
      Sorb; Sorbin homologous domain
      cd11916
      Location:1114 → 1172
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:935 → 989
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1009 → 1066
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    12. XM_006526813.5 → XP_006526876.1  sorbin and SH3 domain-containing protein 1 isoform X38

      UniProtKB/TrEMBL
      A0A286YDN0
      Related
      ENSMUSP00000153489.2, ENSMUST00000226047.2
      Conserved Domains (4) summary
      smart00459
      Location:214 → 260
      Sorb; Sorbin homologous domain
      cd11916
      Location:636 → 694
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:457 → 511
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:531 → 588
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    13. XM_030250825.2 → XP_030106685.1  sorbin and SH3 domain-containing protein 1 isoform X36

      Conserved Domains (5) summary
      smart00459
      Location:223 → 269
      Sorb; Sorbin homologous domain
      cd11916
      Location:645 → 703
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:466 → 520
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:540 → 597
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam06075
      Location:9 → 166
      DUF936; Plant protein of unknown function (DUF936)

    14. XM_006526810.5 → XP_006526873.1  sorbin and SH3 domain-containing protein 1 isoform X35

      See identical proteins and their annotated locations for XP_006526873.1

      UniProtKB/TrEMBL
      E9Q6A3
      Conserved Domains (5) summary
      smart00459
      Location:233 → 279
      Sorb; Sorbin homologous domain
      cd11916
      Location:655 → 713
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:476 → 530
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:550 → 607
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam06075
      Location:9 → 166
      DUF936; Plant protein of unknown function (DUF936)

    15. XM_036161473.1 → XP_036017366.1  sorbin and SH3 domain-containing protein 1 isoform X6

      Conserved Domains (4) summary
      smart00459
      Location:297 → 343
      Sorb; Sorbin homologous domain
      cd11916
      Location:1663 → 1721
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1169 → 1223
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1243 → 1300
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    16. XM_030250820.1 → XP_030106680.1  sorbin and SH3 domain-containing protein 1 isoform X31

      UniProtKB/TrEMBL
      A0A1L7NR63
      Conserved Domains (5) summary
      smart00459
      Location:203 → 249
      Sorb; Sorbin homologous domain
      cd11916
      Location:701 → 759
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:502 → 556
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:576 → 633
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam05109
      Location:16 → 219
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    17. XM_036161491.1 → XP_036017384.1  sorbin and SH3 domain-containing protein 1 isoform X48

      Conserved Domains (5) summary
      smart00459
      Location:327 → 373
      Sorb; Sorbin homologous domain
      cd11916
      Location:805 → 863
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:626 → 680
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:700 → 757
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      pfam05109
      Location:16 → 418
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    18. XM_011247199.1 → XP_011245501.1  sorbin and SH3 domain-containing protein 1 isoform X50

      Conserved Domains (5) summary
      smart00459
      Location:336 → 382
      Sorb; Sorbin homologous domain
      cd11916
      Location:758 → 816
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:579 → 633
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:653 → 710
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:52 → 338
      PHA03307; transcriptional regulator ICP4; Provisional

    19. XM_036161488.1 → XP_036017381.1  sorbin and SH3 domain-containing protein 1 isoform X45

      Conserved Domains (5) summary
      smart00459
      Location:336 → 382
      Sorb; Sorbin homologous domain
      cd11916
      Location:842 → 900
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:663 → 717
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:737 → 794
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:52 → 338
      PHA03307; transcriptional regulator ICP4; Provisional

    20. XM_011247198.1 → XP_011245500.1  sorbin and SH3 domain-containing protein 1 isoform X49

      Conserved Domains (4) summary
      smart00459
      Location:578 → 624
      Sorb; Sorbin homologous domain
      cd11916
      Location:1056 → 1114
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:877 → 931
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:951 → 1008
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    21. XM_036161487.1 → XP_036017380.1  sorbin and SH3 domain-containing protein 1 isoform X44

      Conserved Domains (4) summary
      smart00459
      Location:578 → 624
      Sorb; Sorbin homologous domain
      cd11916
      Location:1140 → 1198
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:961 → 1015
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1035 → 1092
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    22. XM_036161486.1 → XP_036017379.1  sorbin and SH3 domain-containing protein 1 isoform X42

      Conserved Domains (4) summary
      smart00459
      Location:578 → 624
      Sorb; Sorbin homologous domain
      cd11916
      Location:1629 → 1687
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1450 → 1504
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1524 → 1581
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    23. XM_036161483.1 → XP_036017376.1  sorbin and SH3 domain-containing protein 1 isoform X29

      Conserved Domains (4) summary
      smart00459
      Location:233 → 279
      Sorb; Sorbin homologous domain
      cd11916
      Location:711 → 769
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:532 → 586
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:606 → 663
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    24. XM_036161482.1 → XP_036017375.1  sorbin and SH3 domain-containing protein 1 isoform X28

      Conserved Domains (4) summary
      smart00459
      Location:233 → 279
      Sorb; Sorbin homologous domain
      cd11916
      Location:739 → 797
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:560 → 614
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:634 → 691
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    25. XM_036161490.1 → XP_036017383.1  sorbin and SH3 domain-containing protein 1 isoform X47

      Conserved Domains (5) summary
      smart00459
      Location:357 → 403
      Sorb; Sorbin homologous domain
      cd11916
      Location:835 → 893
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:656 → 710
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:730 → 787
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:73 → 359
      PHA03307; transcriptional regulator ICP4; Provisional

    26. XM_036161484.1 → XP_036017377.1  sorbin and SH3 domain-containing protein 1 isoform X34

      Conserved Domains (4) summary
      smart00459
      Location:232 → 278
      Sorb; Sorbin homologous domain
      cd11916
      Location:654 → 712
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:475 → 529
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:549 → 606
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    27. XM_030250819.1 → XP_030106679.1  sorbin and SH3 domain-containing protein 1 isoform X30

      Conserved Domains (4) summary
      smart00459
      Location:232 → 278
      Sorb; Sorbin homologous domain
      cd11916
      Location:702 → 760
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:503 → 557
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:577 → 634
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    28. XM_017318095.1 → XP_017173584.1  sorbin and SH3 domain-containing protein 1 isoform X33

      Conserved Domains (4) summary
      smart00459
      Location:242 → 288
      Sorb; Sorbin homologous domain
      cd11916
      Location:664 → 722
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:485 → 539
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:559 → 616
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    29. XM_011247180.1 → XP_011245482.1  sorbin and SH3 domain-containing protein 1 isoform X7

      Conserved Domains (4) summary
      smart00459
      Location:242 → 288
      Sorb; Sorbin homologous domain
      cd11916
      Location:1608 → 1666
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1114 → 1168
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1188 → 1245
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    30. XM_036161489.1 → XP_036017382.1  sorbin and SH3 domain-containing protein 1 isoform X46

      Conserved Domains (5) summary
      smart00459
      Location:366 → 412
      Sorb; Sorbin homologous domain
      cd11916
      Location:844 → 902
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:665 → 719
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:739 → 796
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:1 → 368
      PHA03307; transcriptional regulator ICP4; Provisional

    31. XM_011247193.1 → XP_011245495.1  sorbin and SH3 domain-containing protein 1 isoform X43

      UniProtKB/TrEMBL
      A0A5F8MPJ2
      Related
      ENSMUSP00000158996.2, ENSMUST00000238831.2
      Conserved Domains (5) summary
      smart00459
      Location:366 → 412
      Sorb; Sorbin homologous domain
      cd11916
      Location:1199 → 1257
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:749 → 803
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:823 → 880
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      PHA03307
      Location:1 → 368
      PHA03307; transcriptional regulator ICP4; Provisional

    32. XM_036161477.1 → XP_036017370.1  sorbin and SH3 domain-containing protein 1 isoform X15

      UniProtKB/TrEMBL
      A0A5F8MPJ2
      Conserved Domains (4) summary
      smart00459
      Location:495 → 541
      Sorb; Sorbin homologous domain
      cd11916
      Location:1328 → 1386
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:878 → 932
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:952 → 1009
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    33. XM_036161476.1 → XP_036017369.1  sorbin and SH3 domain-containing protein 1 isoform X14

      Conserved Domains (4) summary
      smart00459
      Location:598 → 644
      Sorb; Sorbin homologous domain
      cd11916
      Location:1431 → 1489
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:981 → 1035
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1055 → 1112
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    34. XM_011247173.1 → XP_011245475.1  sorbin and SH3 domain-containing protein 1 isoform X2

      Conserved Domains (4) summary
      smart00459
      Location:598 → 644
      Sorb; Sorbin homologous domain
      cd11916
      Location:1964 → 2022
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1470 → 1524
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1544 → 1601
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    35. XM_011247191.1 → XP_011245493.1  sorbin and SH3 domain-containing protein 1 isoform X27

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1030 → 1088
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:851 → 905
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:925 → 982
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    36. XM_030250817.1 → XP_030106677.1  sorbin and SH3 domain-containing protein 1 isoform X26

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1050 → 1108
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:851 → 905
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:925 → 982
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    37. XM_011247190.1 → XP_011245492.1  sorbin and SH3 domain-containing protein 1 isoform X23

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1086 → 1144
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:907 → 961
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:981 → 1038
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    38. XM_030250814.1 → XP_030106674.1  sorbin and SH3 domain-containing protein 1 isoform X20

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1106 → 1164
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:907 → 961
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:981 → 1038
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    39. XM_036161471.1 → XP_036017364.1  sorbin and SH3 domain-containing protein 1 isoform X3

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1924 → 1982
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1430 → 1484
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1504 → 1561
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    40. XM_030250816.1 → XP_030106676.1  sorbin and SH3 domain-containing protein 1 isoform X25

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1058 → 1116
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:879 → 933
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:953 → 1010
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    41. XM_030250815.1 → XP_030106675.1  sorbin and SH3 domain-containing protein 1 isoform X24

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1078 → 1136
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:879 → 933
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:953 → 1010
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    42. XM_030250813.1 → XP_030106673.1  sorbin and SH3 domain-containing protein 1 isoform X19

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1114 → 1172
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:935 → 989
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1009 → 1066
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    43. XM_030250812.1 → XP_030106672.1  sorbin and SH3 domain-containing protein 1 isoform X18

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1134 → 1192
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:935 → 989
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1009 → 1066
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    44. XM_011247175.1 → XP_011245477.1  sorbin and SH3 domain-containing protein 1 isoform X4

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1918 → 1976
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1424 → 1478
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1498 → 1555
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    45. XM_017318093.1 → XP_017173582.1  sorbin and SH3 domain-containing protein 1 isoform X16

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1170 → 1228
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:991 → 1045
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1065 → 1122
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    46. XM_011247183.1 → XP_011245485.1  sorbin and SH3 domain-containing protein 1 isoform X13

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1441 → 1499
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:991 → 1045
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1065 → 1122
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    47. XM_030250808.1 → XP_030106668.1  sorbin and SH3 domain-containing protein 1 isoform X12

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1485 → 1543
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:991 → 1045
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1065 → 1122
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    48. XM_036161472.1 → XP_036017365.1  sorbin and SH3 domain-containing protein 1 isoform X5

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1659 → 1717
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1480 → 1534
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1554 → 1611
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin

    49. XM_011247172.1 → XP_011245474.1  sorbin and SH3 domain-containing protein 1 isoform X1

      Conserved Domains (4) summary
      smart00459
      Location:608 → 654
      Sorb; Sorbin homologous domain
      cd11916
      Location:1974 → 2032
      SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11919
      Location:1480 → 1534
      SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
      cd11922
      Location:1554 → 1611
      SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q62417.2 GenPept UniProtKB/Swiss-Prot:Q62417

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