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    Cask calcium/calmodulin dependent serine protein kinase [ Mus musculus (house mouse) ]

    Gene ID: 12361, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Caskprovided by MGI
    Official Full Name
    calcium/calmodulin dependent serine protein kinaseprovided by MGI
    Primary source
    MGI:MGI:1309489
    See related
    Ensembl:ENSMUSG00000031012 AllianceGenome:MGI:1309489
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LIN-2; Pals3; DXPri1; DXRib1; mLin-2
    Summary
    Enables neurexin family protein binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including calcium ion import; positive regulation of calcium ion import; and positive regulation of transcription by RNA polymerase II. Located in several cellular components, including basolateral plasma membrane; cell-cell junction; and cytosol. Is active in Schaffer collateral - CA1 synapse. Colocalizes with basement membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Orthologous to human CASK (calcium/calmodulin dependent serine protein kinase). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in CNS E18 (RPKM 10.1), whole brain E14.5 (RPKM 9.1) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cask in Genome Data Viewer
    Location:
    X A1.1; X 8.43 cM
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (13383319..13713020, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (13517080..13846783, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46795 Neighboring gene ribosomal protein L10A pseudogene Neighboring gene STARR-seq mESC enhancer starr_46797 Neighboring gene nyctalopin Neighboring gene predicted gene 14506 Neighboring gene predicted gene, 34836 Neighboring gene G protein-coupled receptor 34 Neighboring gene G protein-coupled receptor 82 Neighboring gene nuclear encoded tRNA glutamine 1 (anticodon TTG) Neighboring gene makorin, ring finger protein, 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression of the BNLF-1 oncogene of Epstein-Barr virus in the skin of transgenic mice induces hyperplasia and aberrant expression of keratin 6. Wilson JB, et al. Cell, 1990 Jun 29. PMID 1694724
    2. Specific Deletion of CASK in Pancreatic β Cells Affects Glucose Homeostasis and Improves Insulin Sensitivity in Obese Mice by Reducing Hyperinsulinemia Running Title: β Cell CASK Deletion Reduces Hyperinsulinemia. Liu X, et al. Diabetes, 2021 Oct 21. PMID 34957476
    3. Truncated CASK does not alter skeletal muscle or protein interactors. Sanford JL, et al. Muscle Nerve, 2008 Sep. PMID 18642383
    4. CASK localizes to nuclei in developing skeletal muscle and motor neuron culture models and is agrin-independent. Gardner KL, et al. J Cell Physiol, 2006 Jan. PMID 15965905
    5. Loss of CASK Accelerates Heart Failure Development. Mustroph J, et al. Circ Res, 2021 Apr 16. PMID 33593074, Free PMC Article

    See all (96) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genetic evidence for splicing-dependent structural and functional plasticity in CASK protein.
      Title: Genetic evidence for splicing-dependent structural and functional plasticity in CASK protein.
    2. Loss of CASK Accelerates Heart Failure Development.
      Title: Loss of CASK Accelerates Heart Failure Development.
    3. Haploinsufficiency of X-linked intellectual disability gene CASK induces post-transcriptional changes in synaptic and cellular metabolic pathways.
      Title: Haploinsufficiency of X-linked intellectual disability gene CASK induces post-transcriptional changes in synaptic and cellular metabolic pathways.
    4. CASK can induce the recurrence of Focal and Segmental GlomeruloSclerosis after renal transplantation.
      Title: Circulating CASK is associated with recurrent focal segmental glomerulosclerosis after transplantation.
    5. Authors ascertain that a large fraction of endogenous CNTNAP2, CASK, and GluA1 molecules collectively colocalize together in a tripartite manner. Individual knockdown of either CNTNAP2 or CASK similarly alter GluA1 levels and localization. These findings offer insight to molecular mechanisms underlying GluA1 regulation in interneurons.
      Title: The CNTNAP2-CASK complex modulates GluA1 subcellular distribution in interneurons.
    6. Our results demonstrate that mosaic or global reduction in CASK expression and/or function disproportionately affects retinal ganglion cells (RGCs). CASK expression in RGCs does not appear critical for cell survival, indicating a noncell autonomous role for CASK in the development of optic nerve.
      Title: Non-Cell Autonomous Roles for CASK in Optic Nerve Hypoplasia.
    7. CASK T740A mutation attenuated the interaction between CASK and TBR1 in the brain. However, CASK T740A mice were generally healthy, without obvious defects in brain morphology. The most dramatic defect among the mutant mice was in extinction of associative memory, though acquisition was normal.
      Title: Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice.
    8. CASK phosphorylates neurexin, modulating the interaction of liprin-alpha with the CASK-neurexin1beta-Mint1 complex.
      Title: CASK stabilizes neurexin and links it to liprin-α in a neuronal activity-dependent manner.
    9. Ths data of this study implies that some phenotypic components of CASK heterozygous deletion mutation associated disorders represent systemic manifestation of metabolic stress.
      Title: X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner.
    10. The findings suggest that CASK and the truncated prestin splice isoform contribute to confinement of prestin to the basolateral region of the plasma membrane.
      Title: Generation of somatic electromechanical force by outer hair cells may be influenced by prestin-CASK interaction at the basal junction with the Deiter's cell.
    Submit: New GeneRIF Correction See all GeneRIFs (25)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC7449

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neurexin family protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables neurexin family protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase C binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium ion import IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within establishment of localization in cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cellular response to growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of keratinocyte proliferation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of keratinocyte proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of wound healing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of wound healing ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of calcium ion import IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of insulin secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of neurotransmitter secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of synaptic vesicle exocytosis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of synaptic vesicle exocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in apical dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with basement membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in basement membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with basement membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in basement membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell-cell junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ciliary membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear lamina IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear lamina ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in podocyte foot ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peripheral plasma membrane protein CASK
    Names
    calcium/calmodulin-dependent serine protein kinase (MAGUK family)
    NP_001271432.1
    NP_001271433.1
    NP_001271434.1
    NP_033936.2
    XP_006527623.1
    XP_006527624.1
    XP_011245733.1
    XP_011245734.1
    XP_011245735.1
    XP_011245736.1
    XP_011245737.1
    XP_011245738.1
    XP_011245739.1
    XP_011245740.1
    XP_011245741.1
    XP_011245742.1
    XP_011245743.1
    XP_017173855.1
    XP_017173856.1
    XP_017173857.1
    XP_017173858.1
    XP_017173859.1
    XP_017173860.1
    XP_036017689.1
    XP_036017690.1
    XP_036017691.1
    XP_036017692.1
    XP_036017693.1
    XP_036017694.1
    XP_036017695.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001284503.1 → NP_001271432.1  peripheral plasma membrane protein CASK isoform 1

      See identical proteins and their annotated locations for NP_001271432.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
      Source sequence(s)
      AK136523, AL671117, BU700766, CJ060796, CJ317104, Y17138
      UniProtKB/Swiss-Prot
      A2ADP8, A2ADP9, A2ADQ4, O70588, O70589, Q3UW92
      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 911
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    2. NM_001284504.1 → NP_001271433.1  peripheral plasma membrane protein CASK isoform 2

      See identical proteins and their annotated locations for NP_001271433.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple in-frame differences in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK136523, AL671117, BU700766, CJ060796, CJ317104, Y17138
      UniProtKB/TrEMBL
      B7ZP42, B9EJ23
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:575 → 636
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:692 → 865
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    3. NM_001284505.1 → NP_001271434.1  peripheral plasma membrane protein CASK isoform 3

      See identical proteins and their annotated locations for NP_001271434.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
      Source sequence(s)
      AK136523, AL671117, BU700766, CJ060796, CJ317104, Y17138
      Consensus CDS
      CCDS72343.1
      UniProtKB/TrEMBL
      B7ZP42
      Related
      ENSMUSP00000111098.4, ENSMUST00000115438.10
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 905
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    4. NM_009806.3 → NP_033936.2  peripheral plasma membrane protein CASK isoform 4

      See identical proteins and their annotated locations for NP_033936.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks several alternate in-frame exons in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1.
      Source sequence(s)
      AK136523, AL671117, BU700766, CJ060796, CJ317104, Y17138
      Consensus CDS
      CCDS40878.1
      UniProtKB/TrEMBL
      B7ZP42
      Related
      ENSMUSP00000111096.3, ENSMUST00000115436.9
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 882
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      13383319..13713020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247437.3 → XP_011245739.1  peripheral plasma membrane protein CASK isoform X12

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 922
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    2. XM_036161798.1 → XP_036017691.1  peripheral plasma membrane protein CASK isoform X9

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:599 → 660
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:716 → 929
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    3. XM_011247436.4 → XP_011245738.1  peripheral plasma membrane protein CASK isoform X8

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:599 → 660
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:721 → 934
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    4. XM_036161797.1 → XP_036017690.1  peripheral plasma membrane protein CASK isoform X7

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:727 → 940
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    5. XM_011247435.4 → XP_011245737.1  peripheral plasma membrane protein CASK isoform X6

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 945
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    6. XM_011247432.3 → XP_011245734.1  peripheral plasma membrane protein CASK isoform X2

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:622 → 683
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:739 → 952
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    7. XM_036161799.1 → XP_036017692.1  peripheral plasma membrane protein CASK isoform X11

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 922
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    8. XM_036161796.1 → XP_036017689.1  peripheral plasma membrane protein CASK isoform X5

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:342 → 395
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:482 → 562
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 945
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:400 → 450
      L27; L27 domain

    9. XM_011247440.4 → XP_011245742.1  peripheral plasma membrane protein CASK isoform X21

      See identical proteins and their annotated locations for XP_011245742.1

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:604 → 665
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:721 → 894
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    10. XM_011247433.3 → XP_011245735.1  peripheral plasma membrane protein CASK isoform X3

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 951
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    11. XM_017318366.3 → XP_017173855.1  peripheral plasma membrane protein CASK isoform X10

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:715 → 928
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    12. XM_011247434.3 → XP_011245736.1  peripheral plasma membrane protein CASK isoform X4

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 951
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    13. XM_036161802.1 → XP_036017695.1  peripheral plasma membrane protein CASK isoform X26

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:704 → 877
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    14. XM_017318371.3 → XP_017173860.1  peripheral plasma membrane protein CASK isoform X25

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:587 → 648
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:709 → 882
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    15. XM_017318370.3 → XP_017173859.1  peripheral plasma membrane protein CASK isoform X22

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:599 → 660
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:716 → 889
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    16. XM_017318369.3 → XP_017173858.1  peripheral plasma membrane protein CASK isoform X20

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:599 → 660
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:721 → 894
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    17. XM_017318368.3 → XP_017173857.1  peripheral plasma membrane protein CASK isoform X19

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:727 → 900
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    18. XM_011247439.4 → XP_011245741.1  peripheral plasma membrane protein CASK isoform X18

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:610 → 671
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:732 → 905
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    19. XM_017318367.3 → XP_017173856.1  peripheral plasma membrane protein CASK isoform X14

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:622 → 683
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:739 → 912
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    20. XM_011247431.3 → XP_011245733.1  peripheral plasma membrane protein CASK isoform X1

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:622 → 683
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:744 → 957
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain

    21. XM_006527561.5 → XP_006527624.1  peripheral plasma membrane protein CASK isoform X24

      See identical proteins and their annotated locations for XP_006527624.1

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:710 → 883
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    22. XM_006527560.5 → XP_006527623.1  peripheral plasma membrane protein CASK isoform X16

      See identical proteins and their annotated locations for XP_006527623.1

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 307
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:733 → 906
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    23. XM_011247441.4 → XP_011245743.1  peripheral plasma membrane protein CASK isoform X23

      See identical proteins and their annotated locations for XP_011245743.1

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:593 → 654
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:715 → 888
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    24. XM_036161801.1 → XP_036017694.1  peripheral plasma membrane protein CASK isoform X17

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:733 → 906
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    25. XM_036161800.1 → XP_036017693.1  peripheral plasma membrane protein CASK isoform X15

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:348 → 401
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:616 → 677
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:488 → 568
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:738 → 911
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:406 → 456
      L27; L27 domain

    26. XM_011247438.4 → XP_011245740.1  peripheral plasma membrane protein CASK isoform X13

      UniProtKB/TrEMBL
      B7ZP42
      Conserved Domains (6) summary
      smart00569
      Location:354 → 407
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12081
      Location:622 → 683
      SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
      cd00992
      Location:494 → 574
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd14094
      Location:8 → 313
      STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
      pfam00625
      Location:744 → 917
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:412 → 462
      L27; L27 domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O70589.2 GenPept UniProtKB/Swiss-Prot:O70589

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