YUC6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: YUC6
Primary source: Araport:AT5G25620
Locus tag: AT5G25620
See related: TAIR:AT5G25620
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtYUC6; T14C9.160; T14C9_160; YUCCA6
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

Location:: chromosome: 5

Exon count:: 4

Sequence:: Chromosome: 5; NC_003076.8 (8934941..8938768, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis plants overexpressing YUC6 display enhanced IAA-related phenotypes and exhibit improved drought stress tolerance, low rate of water loss and controlled ROS accumulation under drought and oxidative stresses.
Title: A novel thiol-reductase activity of Arabidopsis YUC6 confers drought tolerance independently of auxin biosynthesis.
Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress.
Title: Transgenic poplar expressing Arabidopsis YUCCA6 exhibits auxin-overproduction phenotypes and increased tolerance to abiotic stress.
YUCCA6 enhances drought tolerance through regulated reactive oxygen species homeostasis
Title: Roles of YUCCAs in auxin biosynthesis and drought stress responses in plants.
a functional YUCCA pathway of auxin biosynthesis in potato
Title: Overexpression of Arabidopsis YUCCA6 in potato results in high-auxin developmental phenotypes and enhanced resistance to water deficit.
YUC6 uses NADPH and oxygen to convert indole-3-pyruvic acid to indole-3-acetic acid.
Title: The biochemical mechanism of auxin biosynthesis by an arabidopsis YUCCA flavin-containing monooxygenase.
Arabidopsis plants over-expressing YUCCA6 displayed dramatic longevity. In addition, plants over-expressing YUCCA6 exhibited classical, delayed dark-induced and hormone-induced senescence in leaves.
Title: YUCCA6 over-expression demonstrates auxin function in delaying leaf senescence in Arabidopsis thaliana.
SPL regulates auxin homeostasis by repressing the transcription of YUC2 and YUC6 and participates in lateral organ morphogenesis.
Title: SPOROCYTELESS modulates YUCCA expression to regulate the development of lateral organs in Arabidopsis.
results identify YUCCA6 as a functional member of the YUCCA family with unique roles in growth and development
Title: yucca6, a dominant mutation in Arabidopsis, affects auxin accumulation and auxin-related phenotypes.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_001203470.1

Supported by ESTs:

NM_122473.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables N,N-dimethylaniline monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables NADP binding	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables indole-3-pyruvate monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables protein-disulfide reductase (NAD(P)H) activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in auxin biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within auxin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within drought recovery	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to ethylene	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to metal ion	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to oxidative stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within somatic embryogenesis	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

Go to the top of the page Help

Preferred Names: Flavin-binding monooxygenase family protein

NP_001190399.2

YUCCA6 (YUC6); FUNCTIONS IN: NADP or NADPH binding, oxidoreductase activity, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity; INVOLVED IN: auxin biosynthetic process; EXPRESSED IN: sepal; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: Flavin-binding monooxygenase family protein (TAIR:AT4G13260.1).

NP_197944.2

YUCCA6 (YUC6); FUNCTIONS IN: NADP or NADPH binding, oxidoreductase activity, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity; INVOLVED IN: auxin biosynthetic process; EXPRESSED IN: sepal; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: Flavin-binding monooxygenase family protein (TAIR:AT4G13260.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

8934941..8938768 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_122473.3 → NP_197944.2 Flavin-binding monooxygenase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_197944.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8VZ59

UniProtKB/TrEMBL

A0A178UES9, A0A5S9Y7R2

Conserved Domains (1) summary

COG2072
Location:33 → 353

CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
NM_001203470.1 → NP_001190399.2 Flavin-binding monooxygenase family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178UES9, A0A5S9Y7R2, F4JY69