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    MAPK6 mitogen-activated protein kinase 6 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173242, updated on 10-Oct-2024

    Summary

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    Gene symbol
    MAPK6
    Gene description
    mitogen-activated protein kinase 6
    Locus tag
    CR201_G0020197
    See related
    Ensembl:ENSPPYG00000006482
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    See MAPK6 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 16 NC_072001.2 (54965341..55012432)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 15 NC_072000.1 (52245003..52291973)

    Chromosome 16 - NC_072001.2Genomic Context describing neighboring genes Neighboring gene tropomodulin 3 Neighboring gene U6 spliceosomal RNA Neighboring gene RNA polymerase-associated protein LEO1-like Neighboring gene uncharacterized LOC129050112 Neighboring gene LEO1 homolog, Paf1/RNA polymerase II complex component Neighboring gene small ribosomal subunit protein uS15-like Neighboring gene BCL2 like 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp459L0825

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 6
    Names
    MAP kinase 6
    MAPK 6
    NP_001126270.1
    XP_009248112.2
    XP_024087937.1
    XP_024087938.1
    XP_054387091.1
    XP_054387092.1
    XP_054387093.1
    XP_063572098.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001132798.1 → NP_001126270.1  mitogen-activated protein kinase 6

      See identical proteins and their annotated locations for NP_001126270.1

      Status: PROVISIONAL

      Source sequence(s)
      CR860018
      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9, H2NN91
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_072001.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      54965341..55012432
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054531117.2 → XP_054387092.1  mitogen-activated protein kinase 6 isoform X2

    2. XM_024232170.3 → XP_024087938.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9, H2NN91
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    3. XM_024232169.3 → XP_024087937.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9, H2NN91
      Related
      ENSPPYP00000007346.3
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    4. XM_063716028.1 → XP_063572098.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9

    5. XM_009249837.4 → XP_009248112.2  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9, H2NN91
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    6. XM_054531118.2 → XP_054387093.1  mitogen-activated protein kinase 6 isoform X2

    7. XM_054531116.2 → XP_054387091.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/Swiss-Prot
      Q5R7U1
      UniProtKB/TrEMBL
      A0A2J8VBS9

    RNA

    1. XR_010137101.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5R7U1.1 GenPept UniProtKB/Swiss-Prot:Q5R7U1

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