U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    damt-1 DNA N6-methyl methyltransferase [ Caenorhabditis elegans ]

    Gene ID: 173970, updated on 19-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    damt-1
    Gene description
    DNA N6-methyl methyltransferase
    Locus tag
    CELE_C18A3.1
    See related
    AllianceGenome:WB:WBGene00015939
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables site-specific DNA-methyltransferase (adenine-specific) activity. Involved in DNA methylation on adenine. Predicted to be active in nucleus. Orthologous to human METTL4 (methyltransferase 4, N6-adenosine). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See damt-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (5720148..5721791)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene putative rRNA-processing protein EBP2 homolog Neighboring gene ncRNA Neighboring gene Zinc/iron permease Neighboring gene Ras-related protein Rab-3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. DNA Methylation on N6-Adenine in C. elegans. Greer EL, et al. Cell, 2015 May 7. PMID 25936839, Free PMC Article
    2. Histone Methylation and Memory of Environmental Stress. Fabrizio P, et al. Cells, 2019 Apr 10. PMID 30974922, Free PMC Article
    3. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Arur S, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19264959, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity, acting on a nucleic acid IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables site-specific DNA-methyltransferase (adenine-specific) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables site-specific DNA-methyltransferase (adenine-specific) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in epigenetic regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA N6-methyladenosine methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA N6-methyl methyltransferase
    NP_495127.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5720148..5721791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062726.3 → NP_495127.1  DNA N6-methyl methyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495127.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09956
      Conserved Domains (1) summary
      cl01947
      Location:185 → 349
      MT-A70; MT-A70
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09956.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools