U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    MITF melanocyte inducing transcription factor [ Bison bison bison ]

    Gene ID: 105004395, updated on 13-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    MITF
    Gene description
    melanocyte inducing transcription factor
    See related
    Ensembl:ENSBBBG00000009019
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bison bison bison (sub-species: bison)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MITF in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011495035.1 (816303..1044759)

    NW_011495035.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 4B Neighboring gene ras-related protein Rab-2B pseudogene Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene uncharacterized LOC105004396

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_011495035.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in melanocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    microphthalmia-associated transcription factor
    Names
    melanogenesis associated transcription factor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Bison_UMD1.0 Primary Assembly

    Genomic

    1. NW_011495035.1 Reference Bison_UMD1.0 Primary Assembly

      Range
      816303..1044759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010861986.1 → XP_010860288.1  microphthalmia-associated transcription factor isoform X2

      See identical proteins and their annotated locations for XP_010860288.1

      UniProtKB/TrEMBL
      A0A6P3J141
      Related
      ENSBBBP00000016252.1, ENSBBBT00000033171.1
      Conserved Domains (3) summary
      cd18926
      Location:294 → 397
      bHLHzip_MITF; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in microphthalmia-associated transcription factor (MITF) and similar proteins
      pfam11851
      Location:391 → 510
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:56 → 194
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    2. XM_010861987.1 → XP_010860289.1  microphthalmia-associated transcription factor isoform X3

      See identical proteins and their annotated locations for XP_010860289.1

      UniProtKB/TrEMBL
      A0A6P3J6R9
      Conserved Domains (3) summary
      cd18926
      Location:293 → 396
      bHLHzip_MITF; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in microphthalmia-associated transcription factor (MITF) and similar proteins
      pfam11851
      Location:390 → 509
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:55 → 193
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    3. XM_010861991.1 → XP_010860293.1  microphthalmia-associated transcription factor isoform X7

      See identical proteins and their annotated locations for XP_010860293.1

      UniProtKB/TrEMBL
      A0A6P3J143
      Related
      ENSBBBP00000027783.1, ENSBBBT00000027834.1
      Conserved Domains (3) summary
      cd00083
      Location:251 → 311
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:339 → 458
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:4 → 142
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    4. XM_010861985.1 → XP_010860287.1  microphthalmia-associated transcription factor isoform X1

      UniProtKB/TrEMBL
      A0A6P3J8J9
      Conserved Domains (3) summary
      cd00083
      Location:319 → 379
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:407 → 520
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:72 → 210
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    5. XM_010861990.1 → XP_010860292.1  microphthalmia-associated transcription factor isoform X6

      UniProtKB/TrEMBL
      A0A6P3J8K3
      Conserved Domains (3) summary
      cd00083
      Location:263 → 323
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:351 → 464
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:72 → 154
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    6. XM_010861988.1 → XP_010860290.1  microphthalmia-associated transcription factor isoform X4

      See identical proteins and their annotated locations for XP_010860290.1

      UniProtKB/TrEMBL
      A0A6P3JA81
      Related
      ENSBBBP00000027779.1, ENSBBBT00000033155.1
      Conserved Domains (3) summary
      cd18926
      Location:278 → 381
      bHLHzip_MITF; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in microphthalmia-associated transcription factor (MITF) and similar proteins
      pfam11851
      Location:375 → 494
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:40 → 178
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    7. XM_010861989.1 → XP_010860291.1  microphthalmia-associated transcription factor isoform X5

      See identical proteins and their annotated locations for XP_010860291.1

      UniProtKB/TrEMBL
      A0A6P3J133
      Conserved Domains (3) summary
      cd00083
      Location:286 → 346
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:374 → 487
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:39 → 177
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.