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    DOT1L DOT1 like histone lysine methyltransferase [ Haliaeetus leucocephalus (bald eagle) ]

    Gene ID: 104831211, updated on 3-Aug-2024

    Summary

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    Gene symbol
    DOT1L
    Gene description
    DOT1 like histone lysine methyltransferase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Haliaeetus leucocephalus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Haliaeetus
    Orthologs
    human mouse all
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    Genomic context

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    See DOT1L in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    100 current Haliaeetus_leucocephalus-4.0 (GCF_000737465.1) Unplaced Scaffold NW_010972651.1 (636281..698109)

    NW_010972651.1Genomic Context describing neighboring genes Neighboring gene MOB kinase activator 3A Neighboring gene adaptor related protein complex 3 subunit delta 1 Neighboring gene pleckstrin homology domain containing J1 Neighboring gene splicing factor 3a subunit 2 Neighboring gene anti-Mullerian hormone

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_010972651.1 Unplaced Scaffold Reference Haliaeetus_leucocephalus-4.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K79 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription regulatory region DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase, H3 lysine-79 specific

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Haliaeetus leucocephalus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Haliaeetus_leucocephalus-4.0

    Genomic

    1. NW_010972651.1 Reference Haliaeetus_leucocephalus-4.0

      Range
      636281..698109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010566629.1 → XP_010564931.1  histone-lysine N-methyltransferase, H3 lysine-79 specific

      Conserved Domains (4) summary
      pfam08123
      Location:91 → 293
      DOT1; Histone methylation protein DOT1
      COG2882
      Location:474 → 607
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      COG5124
      Location:469 → 668
      COG5124; Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]
      pfam15694
      Location:761 → 949
      Med26_M; Mediator complex subunit 26 middle domain
    Nucleotide Protein
    Heading Accession and Version

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