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    TPH1 tryptophan hydroxylase 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 466453, updated on 29-Mar-2024

    Summary

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    Official Symbol
    TPH1provided by VGNC
    Official Full Name
    tryptophan hydroxylase 1provided by VGNC
    Primary source
    VGNC:VGNC:965
    Locus tag
    CK820_G0005659
    See related
    Ensembl:ENSPTRG00000003409
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See TPH1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (22075293..22104144, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (21939433..21968435, complement)

    Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene myogenic differentiation 1 Neighboring gene potassium voltage-gated channel subfamily C member 1 Neighboring gene secretion regulating guanine nucleotide exchange factor Neighboring gene serum amyloid A like 1 Neighboring gene uncharacterized LOC134807292

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Heterogeneous rate of protein evolution in serotonin genes. Andrés AM, et al. Mol Biol Evol, 2007 Dec. PMID 17884826

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tryptophan 5-monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aromatic amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in serotonin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tryptophan 5-hydroxylase 1
    Names
    deafness locus associated putative guanine nucleotide exchange factor
    XP_009458304.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      22075293..22104144 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009460029.5 → XP_009458304.1  tryptophan 5-hydroxylase 1

      See identical proteins and their annotated locations for XP_009458304.1

      UniProtKB/TrEMBL
      A0A2I3SMD3, A0A2J8P4X5, A0A6D2WTU6
      Conserved Domains (1) summary
      TIGR01270
      Location:3 → 439
      Trp_5_monoox; tryptophan 5-monooxygenase, tetrameric
    Nucleotide Protein
    Heading Accession and Version

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