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    INPP5D inositol polyphosphate-5-phosphatase D [ Pan paniscus (pygmy chimpanzee) ]

    Gene ID: 100988546, updated on 8-Mar-2024

    Summary

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    Gene symbol
    INPP5D
    Gene description
    inositol polyphosphate-5-phosphatase D
    See related
    Ensembl:ENSPPAG00000030895
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan paniscus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See INPP5D in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 13 NC_073262.2 (135661459..135810426)
    RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 2B NC_073251.1 (135676418..135825387)

    Chromosome 13 - NC_073262.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134728778 Neighboring gene neuraminidase 2 Neighboring gene autophagy related 16 like 1 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene small Cajal body-specific RNA 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of bone resorption IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of neutrophil differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of B cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
    Names
    inositol polyphosphate-5-phosphatase, 145kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Genomic

    1. NC_073262.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

      Range
      135661459..135810426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003813132.4 → XP_003813180.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2

      Conserved Domains (2) summary
      cd09100
      Location:403 → 709
      INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins
      cd10343
      Location:1 → 102
      SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)

    2. XM_008965726.4 → XP_008963974.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A2R9AEZ4
      Related
      ENSPPAP00000015532.1
      Conserved Domains (2) summary
      cd09100
      Location:404 → 710
      INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins
      cd10343
      Location:1 → 102
      SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
    Nucleotide Protein
    Heading Accession and Version

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