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    FMP45 Fmp45p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851304, updated on 2-Nov-2024

    Summary

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    Official Symbol
    FMP45
    Official Full Name
    Fmp45p
    Primary source
    SGD:S000002381
    Locus tag
    YDL222C
    See related
    AllianceGenome:SGD:S000002381; FungiDB:YDL222C; VEuPathDB:YDL222C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore formation and fungal-type cell wall organization. Located in cell cortex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See FMP45 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (60872..61801, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Whi4p Neighboring gene Hbt1p Neighboring gene telomere-binding protein CDC13 Neighboring gene D-tyrosyl-tRNA(Tyr) deacylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Young ME, et al. Mol Cell Biol, 2002 Feb. PMID 11784867, Free PMC Article
    2. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans. Alvarez FJ, et al. Mol Biol Cell, 2008 Dec. PMID 18799621, Free PMC Article
    3. Cloning of the multicopy suppressor gene SUR7: evidence for a functional relationship between the yeast actin-binding protein Rvs167 and a putative membranous protein. Sivadon P, et al. Yeast, 1997 Jun 30. PMID 9219339
    4. Eisosomes mark static sites of endocytosis. Walther TC, et al. Nature, 2006 Feb 23. PMID 16496001
    5. Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast. Mirisola MG, et al. Biomed J, 2024 Apr. PMID 38154617, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cortical actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in septin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell periphery HDA PubMed 
    is_active_in membrane raft IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fmp45p
    NP_010059.1
    • Integral membrane protein localized to mitochondria; required for sporulation and maintaining sphingolipid content; similar to SUR7; FMP45 has a paralog, YNL194C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      60872..61801 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180282.1 → NP_010059.1  TPA: Fmp45p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010059.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRD3, Q07651
      UniProtKB/TrEMBL
      B3LHA1, B5VF55, C7GSV6, C8Z6P7, N1P5Z4
      Conserved Domains (1) summary
      pfam06687
      Location:22 → 205
      SUR7; SUR7/PalI family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07651.1

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