U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    PYGM glycogen phosphorylase, muscle associated [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100008972, updated on 8-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PYGM
    Gene description
    glycogen phosphorylase, muscle associated
    See related
    Ensembl:ENSOCUG00000002173
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PYGM in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026258873.1 (15684..25973)

    NW_026258873.1Genomic Context describing neighboring genes Neighboring gene splicing factor 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_026258873 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The binding of 2-deoxy-D-glucose 6-phosphate to glycogen phosphorylase b: kinetic and crystallographic studies. Oikonomakos NG, et al. J Mol Biol, 1995 Dec 15. PMID 7500360
    2. Sequence of the carboxyl-terminal 492 residues of rabbit muscle glycogen phosphorylase including the pyridoxal 5'-phosphate binding site. Titani K, et al. Biochemistry, 1978 Dec 26. PMID 728426
    3. Crystallographic analysis of phosphorylase alpha at 2.5 A resolution, a comment on the chemical sequence. Sprang S, et al. Biochemistry, 1978 Dec 26. PMID 728427
    4. Assignment of the amino acid sequence to the crystal structure of glycogen phosphorylase b. Jenkins JA, et al. Biochemistry, 1978 Dec 26. PMID 728428
    5. Domain separation in the activation of glycogen phosphorylase a. Goldsmith EJ, et al. Science, 1989 Aug 4. PMID 2756432

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Effect of arginine on stability and aggregation of muscle glycogen phosphorylase b.
      Title: Effect of arginine on stability and aggregation of muscle glycogen phosphorylase b.
    2. These results suggest that some conformational changes have taken place in the maltooligosaccharide-binding region of the GP catalytic site during allosteric regulation.
      Title: Probing the catalytic site of rabbit muscle glycogen phosphorylase using a series of specifically modified maltohexaose derivatives.
    3. The formation of a complex between the denatured monomeric form of Phb and the dissociated forms of GroEL is detected during heating at 46 degrees C.
      Title: Effect of GroEL on thermal aggregation of glycogen phosphorylase b from rabbit skeletal muscle.
    4. alpha-crystallin interacts with the intermediates of unfolding of the Phb molecule
      Title: Kinetics of thermal aggregation of glycogen phosphorylase b from rabbit skeletal muscle: mechanism of protective action of alpha-crystallin.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glycogen phosphorylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycogen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glycogen phosphorylase, muscle form
    Names
    myophosphorylase
    phosphorylase, glycogen, muscle
    NP_001075653.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082184.1 → NP_001075653.1  glycogen phosphorylase, muscle form

      See identical proteins and their annotated locations for NP_001075653.1

      Status: PROVISIONAL

      Source sequence(s)
      X04265
      UniProtKB/Swiss-Prot
      P00489
      UniProtKB/TrEMBL
      B7NZI0
      Related
      ENSOCUP00000001880.3, ENSOCUT00000002177.3
      Conserved Domains (2) summary
      cd04300
      Location:29 → 828
      GT1_Glycogen_Phosphorylase; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of ...
      TIGR02093
      Location:32 → 828
      P_ylase; glycogen/starch/alpha-glucan phosphorylases

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NW_026258873.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      15684..25973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P00489.3 GenPept UniProtKB/Swiss-Prot:P00489

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.