pter phosphotriesterase related [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pterprovided by ZNC
Official Full Name: phosphotriesterase relatedprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060825-190
See related: Ensembl:ENSDARG00000063375 AllianceGenome:ZFIN:ZDB-GENE-060825-190
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153666
Summary: Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Predicted to act upstream of or within catabolic process. Orthologous to human PTER (phosphotriesterase related). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (3603712..3614005, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (3772533..3782826, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on ester bonds	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: phosphotriesterase-related protein

Names: parathion hydrolase-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045381.2 → NP_001038846.2 phosphotriesterase-related protein

Status: VALIDATED

Source sequence(s)

CK141754, EH450120, EH572300

UniProtKB/Swiss-Prot

A2BII3, Q0P3Z2

UniProtKB/TrEMBL

A0A8M1NAM0, F1RBR6

Related

ENSDARP00000099334.1, ENSDART00000110399.3

Conserved Domains (1) summary

cd00530
Location:21 → 346

PTE; Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site ...