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    APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B [ Pan troglodytes (chimpanzee) ]

    Gene ID: 743891, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APOBEC3Bprovided by VGNC
    Official Full Name
    apolipoprotein B mRNA editing enzyme catalytic subunit 3Bprovided by VGNC
    Primary source
    VGNC:VGNC:12807
    See related
    Ensembl:ENSPTRG00000014384
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human all
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    Genomic context

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    See APOBEC3B in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (40985214..40995104)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (34017609..34027499)

    Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene chromobox 6 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3A Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3C Neighboring gene uncharacterized LOC134809669 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential L1 regulation in pluripotent stem cells of humans and apes. Marchetto MCN, et al. Nature, 2013 Nov 28. PMID 24153179, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytidine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA cytosine deamination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytidine to uridine editing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA dC->dU-editing enzyme APOBEC-3B
    Names
    apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
    apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
    NP_001276568.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289639.1 → NP_001276568.1  DNA dC->dU-editing enzyme APOBEC-3B

      See identical proteins and their annotated locations for NP_001276568.1

      Status: PROVISIONAL

      Source sequence(s)
      KF651168
      UniProtKB/TrEMBL
      K7AN26, K7BTL7
      Related
      ENSPTRP00000082459.1, ENSPTRT00000088480.1
      Conserved Domains (3) summary
      cd01283
      Location:8 → 158
      cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
      pfam05240
      Location:129 → 174
      APOBEC_C; APOBEC-like C-terminal domain
      pfam08210
      Location:17 → 187
      APOBEC_N; APOBEC-like N-terminal domain

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      40985214..40995104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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