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    DARS2 aspartyl-tRNA synthetase 2, mitochondrial [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173764, updated on 10-Oct-2024

    Summary

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    Gene symbol
    DARS2
    Gene description
    aspartyl-tRNA synthetase 2, mitochondrial
    Locus tag
    CR201_G0028952
    See related
    Ensembl:ENSPPYG00000000493
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    See DARS2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 1 NC_071985.2 (76164042..76197550, complement)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 1 NC_071985.1 (76157221..76197529, complement)

    Chromosome 1 - NC_071985.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100936956 Neighboring gene small nucleolar RNA SNORD47 Neighboring gene small nucleolar RNA SNORD81 Neighboring gene centromere protein L Neighboring gene kelch like family member 20 Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene ankyrin repeat domain 45 Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp469I0720

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aspartate-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in aspartyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aspartate--tRNA ligase, mitochondrial
    NP_001361118.1
    XP_054394182.1
    XP_054394197.1
    XP_054394208.1
    XP_063575508.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374189.2 → NP_001361118.1  aspartate--tRNA ligase, mitochondrial

      Status: VALIDATED

      Source sequence(s)
      JAQQLQ020000001
      UniProtKB/TrEMBL
      A0A663DB70, A0A8I5UW55
      Conserved Domains (1) summary
      PRK00476
      Location:50 → 633
      aspS; aspartyl-tRNA synthetase; Validated

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071985.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      76164042..76197550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063719438.1 → XP_063575508.1  aspartate--tRNA ligase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0A2J8UBV6, H2N4M9

    2. XM_054538207.2 → XP_054394182.1  aspartate--tRNA ligase, mitochondrial isoform X2

      UniProtKB/TrEMBL
      A0A8I5UB08

    3. XM_054538222.2 → XP_054394197.1  aspartate--tRNA ligase, mitochondrial isoform X3

    4. XM_054538233.2 → XP_054394208.1  aspartate--tRNA ligase, mitochondrial isoform X4

      UniProtKB/TrEMBL
      A0A8I5U5F8

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001133290.1: Suppressed sequence

      Description
      NM_001133290.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version

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