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    CD80 CD80 molecule [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102140078, updated on 10-Oct-2024

    Summary

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    Gene symbol
    CD80
    Gene description
    CD80 molecule
    See related
    Ensembl:ENSMFAG00000032987
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CD80 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 2 NC_088376.1 (163610233..163652259)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 2 NC_052256.1 (39385103..39418223, complement)

    Chromosome 2 - NC_088376.1Genomic Context describing neighboring genes Neighboring gene phospholipase A1 member A Neighboring gene uncharacterized LOC123571714 Neighboring gene ADP-ribosylarginine hydrolase Neighboring gene uncharacterized LOC135964440 Neighboring gene cysteine and glycine-rich protein 2-like Neighboring gene translocase of inner mitochondrial membrane domain containing 1 Neighboring gene protein O-glucosyltransferase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables coreceptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell costimulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-lymphocyte activation antigen CD80

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088376.1 Reference T2T-MFA8v1.0

      Range
      163610233..163652259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005548065.4 → XP_005548122.1  T-lymphocyte activation antigen CD80

      See identical proteins and their annotated locations for XP_005548122.1

      UniProtKB/TrEMBL
      A0A2K5V5I3, A0A7N9D5C9, G7NXN7
      Related
      ENSMFAP00000019988.1
      Conserved Domains (3) summary
      smart00410
      Location:37 → 138
      IG_like; Immunoglobulin like
      pfam08205
      Location:142 → 227
      C2-set_2; CD80-like C2-set immunoglobulin domain
      cl11960
      Location:37 → 134
      Ig; Immunoglobulin domain

    2. XM_065539167.1 → XP_065395239.1  T-lymphocyte activation antigen CD80

      UniProtKB/TrEMBL
      A0A2K5V5I3, A0A7N9D5C9
    Nucleotide Protein
    Heading Accession and Version

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