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    frmd4bb FERM domain containing 4Bb [ Oreochromis niloticus (Nile tilapia) ]

    Gene ID: 100700531, updated on 8-Mar-2024

    Summary

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    Gene symbol
    frmd4bb
    Gene description
    FERM domain containing 4Bb
    See related
    Ensembl:ENSONIG00000016949
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oreochromis niloticus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
    Also known as
    frmd4b
    Orthologs
    zebrafish all
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    Genomic context

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    See frmd4bb in Genome Data Viewer
    Location:
    chromosome: LG20
    Exon count:
    24
    Annotation release Status Assembly LG Location
    104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG20 NC_031984.2 (11657380..11677484, complement)
    103 previous assembly ASM185804v2 (GCF_001858045.1) LG20 NC_031984.1 (12159287..12179426, complement)

    Linkage Group LG20 - NC_031984.2Genomic Context describing neighboring genes Neighboring gene NEDD8-activating enzyme E1 catalytic subunit Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 5 Neighboring gene leiomodin 3 (fetal) Neighboring gene microphthalmia-associated transcription factor Neighboring gene 2-epi-5-epi-valiolone synthase Neighboring gene forkhead box protein P1-B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in establishment of epithelial cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FERM domain-containing protein 4B
    Names
    FERM domain containing 4B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference O_niloticus_UMD_NMBU Primary Assembly

    Genomic

    1. NC_031984.2 Reference O_niloticus_UMD_NMBU Primary Assembly

      Range
      11657380..11677484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005448574.3 → XP_005448631.1  FERM domain-containing protein 4B isoform X3

      UniProtKB/TrEMBL
      I3KJT1
      Conserved Domains (6) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam00373
      Location:94 → 206
      FERM_M; FERM central domain
      pfam03938
      Location:363 → 408
      OmpH; Outer membrane protein (OmpH-like)
      pfam09379
      Location:9 → 70
      FERM_N; FERM N-terminal domain
      pfam11819
      Location:347 → 474
      DUF3338; Domain of unknown function (DUF3338)

    2. XM_005448573.3 → XP_005448630.1  FERM domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A669C3Y3
      Related
      ENSONIP00000042825.1, ENSONIT00000076700.1
      Conserved Domains (6) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam00373
      Location:94 → 206
      FERM_M; FERM central domain
      pfam03938
      Location:363 → 408
      OmpH; Outer membrane protein (OmpH-like)
      pfam09379
      Location:9 → 70
      FERM_N; FERM N-terminal domain
      pfam11819
      Location:347 → 474
      DUF3338; Domain of unknown function (DUF3338)

    3. XM_005448572.3 → XP_005448629.1  FERM domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      I3KJT1
      Related
      ENSONIP00000021376.2, ENSONIT00000021395.2
      Conserved Domains (4) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13191
      Location:202 → 312
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      cd17200
      Location:3 → 91
      FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
      pfam11819
      Location:343 → 473
      DUF3338; Domain of unknown function (DUF3338)
    Nucleotide Protein
    Heading Accession and Version

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