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    eloca elongin C paralog a [ Danio rerio (zebrafish) ]

    Gene ID: 447935, updated on 2-Nov-2024

    Summary

    Official Symbol
    elocaprovided by ZNC
    Official Full Name
    elongin C paralog aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-120
    See related
    Ensembl:ENSDARG00000045355 AllianceGenome:ZFIN:ZDB-GENE-040912-120
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tceb1; tceb1a; zgc:101879
    Summary
    Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of elongin complex. Orthologous to human ELOC (elongin C). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Try the new Transcript table

    Genomic context

    See eloca in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (12983456..12988855)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (12839005..12844436)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene fat storage inducing transmembrane protein 1 Neighboring gene ddb1 and cul4 associated factor 11 Neighboring gene ubiquitin conjugating enzyme E2 Wb Neighboring gene staufen double-stranded RNA binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of elongin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    elongin C paralog a
    Names
    transcription elongation factor B (SIII), polypeptide 1a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004673.1NP_001004673.1  elongin C paralog a

      See identical proteins and their annotated locations for NP_001004673.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081421
      UniProtKB/TrEMBL
      F6P504, F6P7K8, Q66IB1
      Related
      ENSDARP00000066699.4, ENSDART00000066700.5
      Conserved Domains (1) summary
      smart00512
      Location:17113
      Skp1; Found in Skp1 protein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      12983456..12988855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217058.1XP_068073159.1  elongin C paralog a isoform X2

    2. XM_005162638.4XP_005162695.1  elongin C paralog a isoform X1

      See identical proteins and their annotated locations for XP_005162695.1

      UniProtKB/TrEMBL
      F6P504, F6P7K8, Q66IB1
      Related
      ENSDARP00000121970.1, ENSDART00000146911.3
      Conserved Domains (1) summary
      smart00512
      Location:17113
      Skp1; Found in Skp1 protein family
    3. XM_005162640.4XP_005162697.1  elongin C paralog a isoform X2

      See identical proteins and their annotated locations for XP_005162697.1

      UniProtKB/TrEMBL
      A0A8M2B9H7, E9QCI1
      Related
      ENSDARP00000117248.1, ENSDART00000145214.3
      Conserved Domains (1) summary
      smart00512
      Location:16112
      Skp1; Found in Skp1 protein family

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395167.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      84984..90339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)