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    Efcab11 EF-hand calcium binding domain 11 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101715394, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Efcab11
    Gene description
    EF-hand calcium binding domain 11
    Locus tag
    GW7_07038
    See related
    Ensembl:ENSHGLG00000011766
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Efcab11 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (12414914..12601221)

    NW_004624734.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 13 Neighboring gene tyrosyl-DNA phosphodiesterase 1 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene uncharacterized LOC110345947 Neighboring gene forkhead box N3 Neighboring gene uncharacterized LOC110345960 Neighboring gene uncharacterized LOC110345962

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    EF-hand calcium-binding domain-containing protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      12414914..12601221
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021245261.1 → XP_021100920.1  EF-hand calcium-binding domain-containing protein 11 isoform X5

      Conserved Domains (1) summary
      cl25352
      Location:3 → 90
      EFh_PEF; The penta-EF hand (PEF) family

    2. XM_021245258.1 → XP_021100917.1  EF-hand calcium-binding domain-containing protein 11 isoform X5

      Conserved Domains (1) summary
      cl25352
      Location:3 → 90
      EFh_PEF; The penta-EF hand (PEF) family

    3. XM_021245235.1 → XP_021100894.1  EF-hand calcium-binding domain-containing protein 11 isoform X1

      Conserved Domains (1) summary
      cl25352
      Location:16 → 138
      EFh_PEF; The penta-EF hand (PEF) family

    4. XM_021245246.1 → XP_021100905.1  EF-hand calcium-binding domain-containing protein 11 isoform X3

      UniProtKB/TrEMBL
      G5BK45
      Conserved Domains (1) summary
      cl25352
      Location:16 → 158
      EFh_PEF; The penta-EF hand (PEF) family

    5. XM_004837076.3 → XP_004837133.1  EF-hand calcium-binding domain-containing protein 11 isoform X2

      UniProtKB/TrEMBL
      G5BK45
      Related
      ENSHGLP00000016430.1, ENSHGLT00000016599.1
      Conserved Domains (1) summary
      COG5126
      Location:16 → 162
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    6. XM_021245240.1 → XP_021100899.1  EF-hand calcium-binding domain-containing protein 11 isoform X2

      UniProtKB/TrEMBL
      G5BK45
      Related
      ENSHGLP00000016429.1, ENSHGLT00000016598.1
      Conserved Domains (1) summary
      COG5126
      Location:16 → 162
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    7. XM_004837077.2 → XP_004837134.1  EF-hand calcium-binding domain-containing protein 11 isoform X4

      UniProtKB/TrEMBL
      G5BK45
      Conserved Domains (3) summary
      pfam13405
      Location:95 → 121
      EF-hand_6; EF-hand domain
      pfam13499
      Location:25 → 83
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:25 → 84
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RNA

    1. XR_002389645.1 RNA Sequence

    2. XR_002389646.1 RNA Sequence

    3. XR_204851.2 RNA Sequence

    4. XR_002389648.1 RNA Sequence

    5. XR_002389647.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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