slc11a1 solute carrier family 11 member 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: slc11a1provided by Xenbase
Official Full Name: solute carrier family 11 member 1provided by Xenbase
Primary source: Xenbase:XB-GENE-482302
See related: Ensembl:ENSXETG00000014937 AllianceGenome:Xenbase:XB-GENE-482302
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable metal ion transmembrane transporter activity. Predicted to act upstream of or within iron ion transport. Predicted to be located in late endosome membrane and lysosomal membrane. Human ortholog(s) of this gene implicated in several diseases, including Buruli ulcer disease; autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	9	NC_030685.2 (82221194..82243399)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	9	NC_030685.1 (77008906..77033039)

Chromosome 9 - NC_030685.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables metal ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within iron ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within metal ion transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in lysosomal membrane	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

Names: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

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The following sections contain reference sequences that belong to a specific genome build. Explain