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    TDE_RS12600 phosphatidylglycerol lysyltransferase domain-containing protein [ Treponema denticola ATCC 35405 ]

    Gene ID: 2741120, updated on 1-May-2024

    Summary

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    Gene symbol
    TDE_RS12600
    Gene description
    phosphatidylglycerol lysyltransferase domain-containing protein
    Locus tag
    TDE_RS12600
    Gene type
    protein coding
    Organism
    Treponema denticola ATCC 35405 (strain: ATCC 35405, type-material: type strain of Treponema denticola)
    Lineage
    Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae; Treponema
    Old locus tag
    TDE2675; TDE_2675
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    Genomic context

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    Sequence:
    NC_002967.9 (2713514..2714404)

    NC_002967.9Genomic Context describing neighboring genes Neighboring gene DUF2715 domain-containing protein Neighboring gene DUF2715 domain-containing protein Neighboring gene threonine synthase Neighboring gene hypothetical protein Neighboring gene alpha-amylase family glycosyl hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002967.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance. Ernst CM, et al. mBio, 2018 Dec 18. PMID 30563904, Free PMC Article
    2. The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides. Maloney E, et al. PLoS Pathog, 2009 Jul. PMID 19649276, Free PMC Article
    3. MprF-mediated biosynthesis of lysylphosphatidylglycerol, an important determinant in staphylococcal defensin resistance. Staubitz P, et al. FEMS Microbiol Lett, 2004 Feb 9. PMID 14769468
    4. Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes. Seshadri R, et al. Proc Natl Acad Sci U S A, 2004 Apr 13. PMID 15064399, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    phosphatidylglycerol lysyltransferase domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002967.9 Reference assembly

      Range
      2713514..2714404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002667127.1 MULTISPECIES: phosphatidylglycerol lysyltransferase domain-containing protein [Treponema]

      See identical proteins and their annotated locations for WP_002667127.1

      UniProtKB/TrEMBL
      A0A0F6MRJ2, Q73JA0
    Nucleotide Protein
    Heading Accession and Version

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