GAPDH glyceraldehyde-3-phosphate dehydrogenase [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: GAPDHprovided by CGNC
Official Full Name: glyceraldehyde-3-phosphate dehydrogenaseprovided by CGNC
Primary source: CGNC:49077
See related: Ensembl:ENSGALG00010022038
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: GAPD; KNC-NDS6
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (76902321..76906238)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (77102398..77106314)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

After knockdown of GPI, several genes involved in the glycolysis/gluconeogenesis pathways were altered in the chicken germ cells. However, expression of the housekeeping gene GAPDH that is also involved in the pathways did not differ.
Title: Expression and knockdown analysis of glucose phosphate isomerase in chicken primordial germ cells.
Results show that despite being commonly used housekeeping genes neither GAPDH mRNA nor beta-actin mRNA is expressed in all cell types or tissues at high levels. Strikingly, expression levels are very low in some organs.
Title: Histological evidence: housekeeping genes beta-actin and GAPDH are of limited value for normalization of gene expression.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

PMC104479P2 (e-PCR)
- UniSTS:270113

GAPDsts1 (e-PCR), detects polymorphism
- UniSTS:279843

GAPDsts2 (e-PCR), detects polymorphism
- UniSTS:279844

GAPDsts3 (e-PCR), detects polymorphism
- UniSTS:279845

PMC122568P2 (e-PCR)
- UniSTS:270398

GDB:376732 (e-PCR)
- UniSTS:157065

PMC115884P2 (e-PCR)
- UniSTS:270303

PMC128235P1 (e-PCR)
- UniSTS:270574

PMC329392P1 (e-PCR)
- UniSTS:273149

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info	PubMed
enables NADP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glucose metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glyceraldehyde-3-phosphate dehydrogenase

Names: peptidyl-cysteine S-nitrosylase GAPDH

NP_989636.1

EC 1.2.1.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.