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    atxA anthrax toxin expression trans-acting transcriptional regulator AtxA [ Bacillus anthracis str. 'Ames Ancestor' ]

    Gene ID: 45025503, updated on 1-Aug-2024

    Summary

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    Gene symbol
    atxA
    Gene description
    anthrax toxin expression trans-acting transcriptional regulator AtxA
    Locus tag
    GBAA_RS29060
    Gene type
    protein coding
    RefSeq status
    PIPELINE
    Organism
    Bacillus anthracis str. 'Ames Ancestor' (strain: Ames Ancestor; A2084)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group
    Old locus tag
    GBAA_pXO1_0146
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    Genomic context

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    Location:
    plasmid: pXO1
    Sequence:
    NC_007322.2 (127765..129192, complement)

    NC_007322.2Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene histidine kinase N-terminal domain-containing protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007322.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The anthrax toxin activator gene atxA is associated with CO2-enhanced non-toxin gene expression in Bacillus anthracis. Hoffmaster AR, et al. Infect Immun, 1997 Aug. PMID 9234759, Free PMC Article
    2. Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis. Uchida I, et al. J Bacteriol, 1993 Sep. PMID 8366021, Free PMC Article
    3. Bacillus anthracis Virulence Regulator AtxA Binds Specifically to the pagA Promoter Region. McCall RM, et al. J Bacteriol, 2019 Dec 1. PMID 31570528, Free PMC Article
    4. Sequence analysis of the genes encoding for the major virulence factors of Bacillus anthracis vaccine strain 'Carbosap'. Adone R, et al. J Appl Microbiol, 2002. PMID 12067380
    5. The complete genome sequence of Bacillus anthracis Ames "Ancestor". Ravel J, et al. J Bacteriol, 2009 Jan. PMID 18952800, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bacillus anthracis virulence regulator AtxA binds specifically to the pagA promoter region.
      Title: Bacillus anthracis Virulence Regulator AtxA Binds Specifically to the pagA Promoter Region.
    Submit: New GeneRIF Correction

    General protein information

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    Preferred Names
    anthrax toxin expression trans-acting transcriptional regulator AtxA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007322.2 Reference assembly

      Range
      127765..129192 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000957312.1 MULTISPECIES: anthrax toxin expression trans-acting transcriptional regulator AtxA [Bacillus]

      See identical proteins and their annotated locations for WP_000957312.1

      Status: PIPELINE

      UniProtKB/Swiss-Prot
      Q44636, Q84J36, Q933U4, Q933V7, Q9RQT9
      UniProtKB/TrEMBL
      A0A125YA55
      Conserved Domains (3) summary
      COG3711
      Location:13 → 380
      BglG; Transcriptional antiterminator [Transcription]
      pfam05043
      Location:75 → 160
      Mga; Mga helix-turn-helix domain
      cl10014
      Location:412 → 475
      PTS_IIB; subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic domains ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q44636.2

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