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    FGR FGR proto-oncogene, Src family tyrosine kinase [ Gorilla gorilla gorilla (western lowland gorilla) ]

    Gene ID: 101140064, updated on 10-Oct-2024

    Summary

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    Gene symbol
    FGR
    Gene description
    FGR proto-oncogene, Src family tyrosine kinase
    See related
    Ensembl:ENSGGOG00000000775
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gorilla gorilla gorilla (sub-species: gorilla)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
    Orthologs
    human mouse all
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    Genomic context

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    See FGR in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 1 NC_073224.2 (212316940..212340166)
    RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 1 NC_073224.1 (33706824..33730129, complement)

    Chromosome 1 - NC_073224.2Genomic Context describing neighboring genes Neighboring gene interferon alpha inducible protein 6 Neighboring gene translation machinery-associated protein 7-like Neighboring gene AT-hook DNA binding motif containing 1 Neighboring gene uncharacterized LOC129533947 Neighboring gene uncharacterized LOC129533948

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase Fgr

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Genomic

    1. NC_073224.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

      Range
      212316940..212340166
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_055389267.2 → XP_055245242.1  tyrosine-protein kinase Fgr

      UniProtKB/TrEMBL
      G3QER4

    2. XM_004025267.4 → XP_004025316.1  tyrosine-protein kinase Fgr

      UniProtKB/TrEMBL
      A0A2I2Z3X5, G3QER4
      Related
      ENSGGOP00000000763.2
      Conserved Domains (3) summary
      cd10367
      Location:140 → 240
      SH2_Src_Fgr; Src homology 2 (SH2) domain found in Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Fgr
      cl17036
      Location:80 → 137
      SH3; Src Homology 3 domain superfamily
      cl21453
      Location:267 → 514
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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