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    VIM5 zinc finger (C3HC4-type RING finger) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842155, updated on 18-Sep-2024

    Summary

    Official Symbol
    VIM5
    Official Full Name
    zinc finger (C3HC4-type RING finger) family protein
    Primary source
    TAIR:AT1G57800
    Locus tag
    AT1G57800
    See related
    Araport:AT1G57800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12K22.15; F12K22_15; ORTH3; ORTHRUS 3; VARIANT IN METHYLATION 5
    Summary
    predicted to encode a protein with an N-terminal PHD domain and two RING domains surrounding an SRA domain. Attempts to isolate ORTH3/VIM5 cDNA through RT-PCR were unsuccessful and only one Arabidopsis EST is associated with this locus. A paternally expressed imprinted gene.
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    Genomic context

    See VIM5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (21408623..21412283, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Zinc finger (C3HC4-type RING finger) family protein

    General gene information

    NM_001333805.1
    NM_104575.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables methyl-CpG binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables methyl-CpNpG binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables methyl-CpNpN binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    zinc finger (C3HC4-type RING finger) family protein
    NP_176091.2
    • VARIANT IN METHYLATION 5 (VIM5); FUNCTIONS IN: zinc ion binding; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: SRA-YDG (InterPro:IPR003105), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011); BEST Arabidopsis thaliana protein match is: Zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57820.1); Has 5254 Blast hits to 5127 proteins in 1563 species: Archae - 0; Bacteria - 14; Metazoa - 4362; Fungi - 258; Plants - 447; Viruses - 0; Other Eukaryotes - 173 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21408623..21412283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104575.3NP_176091.2  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176091.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FVS2
      UniProtKB/TrEMBL
      A0A654EPA5
      Conserved Domains (3) summary
      smart00249
      Location:1460
      PHD; PHD zinc finger
      cd00162
      Location:140200
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam02182
      Location:274433
      SAD_SRA; SAD/SRA domain
    2. NM_001333805.1NP_001321213.1  zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQ73, A0A654EPA5