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    VPS41 VPS41 subunit of HOPS complex [ Pan troglodytes (chimpanzee) ]

    Gene ID: 463365, updated on 10-Oct-2024

    Summary

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    Official Symbol
    VPS41provided by VGNC
    Official Full Name
    VPS41 subunit of HOPS complexprovided by VGNC
    Primary source
    VGNC:VGNC:8787
    Locus tag
    CK820_G0047874
    See related
    Ensembl:ENSPTRG00000019104
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See VPS41 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (44508457..44690119, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (42149099..42330740, complement)

    Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene protein CFAP144P1 Neighboring gene POU class 6 homeobox 2 Neighboring gene uncharacterized LOC107975770 Neighboring gene small nucleolar RNA SNORA20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosomal vesicle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to vacuole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of HOPS complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar protein sorting-associated protein 41 homolog
    Names
    VPS41, HOPS complex subunit
    vacuolar protein sorting 41 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      44508457..44690119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_519057.8 → XP_519057.3  vacuolar protein sorting-associated protein 41 homolog isoform X1

      See identical proteins and their annotated locations for XP_519057.3

      UniProtKB/TrEMBL
      A0A2I3S1F4, A0A2I3SC42, A0A2J8PZ82, A0A6D2W0G8
      Related
      ENSPTRP00000074062.1
      Conserved Domains (3) summary
      smart00299
      Location:571 → 708
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:138 → 169
      7WD40; WD40 repeat [structural motif]
      cd16690
      Location:787 → 841
      RING-H2_Vps41; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 41 (Vps41) and similar proteins

    2. XM_009452921.5 → XP_009451196.1  vacuolar protein sorting-associated protein 41 homolog isoform X2

      UniProtKB/TrEMBL
      A0A2I3S1F4
      Related
      ENSPTRP00000070418.1
      Conserved Domains (3) summary
      smart00299
      Location:558 → 695
      CLH; Clathrin heavy chain repeat homology
      sd00039
      Location:125 → 156
      7WD40; WD40 repeat [structural motif]
      cd16690
      Location:774 → 828
      RING-H2_Vps41; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 41 (Vps41) and similar proteins

    3. XM_063815336.1 → XP_063671406.1  vacuolar protein sorting-associated protein 41 homolog isoform X3

    Nucleotide Protein
    Heading Accession and Version

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