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    CD1B2 CD1b2 molecule [ Equus caballus (horse) ]

    Gene ID: 100056393, updated on 15-Aug-2024

    Summary

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    Gene symbol
    CD1B2
    Gene description
    CD1b2 molecule
    See related
    Ensembl:ENSECAG00000016614
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
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    Genomic context

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    See CD1B2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (35222965..35227323, complement)

    Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily X member 1F, pseudogene Neighboring gene CD1e molecule Neighboring gene CD1c molecule Neighboring gene olfactory receptor family 10 subfamily X member 1E

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009148.3 Chromosome 5 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The equine CD1 gene family is the largest and most diverse yet identified. Dossa RG, et al. Immunogenetics, 2014 Jan. PMID 24196432
    2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endogenous lipid antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables exogenous lipid antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipopeptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation, endogenous lipid antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antigen processing and presentation, exogenous lipid antigen via MHC class Ib IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell mediated cytotoxicity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CD1b2 molecule
    Names
    CD1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001246676.1 → NP_001233605.1  CD1b2 molecule precursor

      See identical proteins and their annotated locations for NP_001233605.1

      Status: PROVISIONAL

      Source sequence(s)
      JF749876
      UniProtKB/TrEMBL
      F6YHL4
      Related
      ENSECAP00000014357.2, ENSECAT00000017658.2
      Conserved Domains (2) summary
      cd07698
      Location:203 → 295
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      cl08246
      Location:19 → 198
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009148.3 Reference EquCab3.0 Primary Assembly

      Range
      35222965..35227323 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023640267.1 → XP_023496035.1  CD1b2 molecule isoform X1

      Conserved Domains (2) summary
      cd07698
      Location:280 → 372
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      cl08246
      Location:98 → 275
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    Nucleotide Protein
    Heading Accession and Version

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