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    lrrc45 leucine rich repeat containing 45 [ Danio rerio (zebrafish) ]

    Gene ID: 100329452, updated on 17-Aug-2024

    Summary

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    Official Symbol
    lrrc45provided by ZNC
    Official Full Name
    leucine rich repeat containing 45provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-121214-317
    See related
    Ensembl:ENSDARG00000014005 AllianceGenome:ZFIN:ZDB-GENE-121214-317
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-202c14.4
    Summary
    Orthologous to human LRRC45 (leucine rich repeat containing 45). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See lrrc45 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (2993495..3020627)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (2958773..2985054)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene FAM20A golgi associated secretory pathway pseudokinase Neighboring gene WD repeat-containing protein 49-like Neighboring gene Rac family small GTPase 3b Neighboring gene dicarbonyl/L-xylulose reductase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation. Letelier J, et al. Proc Natl Acad Sci U S A, 2018 Apr 17. PMID 29610331, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 45

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      2993495..3020627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002663878.5 → XP_002663924.1  leucine-rich repeat-containing protein 45

      UniProtKB/TrEMBL
      A0A0R4IU41, A0A8M1RDW0
      Related
      ENSDARP00000138152.1, ENSDART00000082297.6
      Conserved Domains (5) summary
      cd00116
      Location:21 → 219
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:39 → 63
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08537
      Location:203 → 361
      NBP1; Fungal Nap binding protein NBP1
      pfam15290
      Location:436 → 533
      Syntaphilin; Golgi-localized syntaxin-1-binding clamp
      pfam17045
      Location:398 → 655
      CEP63; Centrosomal protein of 63 kDa

    RNA

    1. XR_002459733.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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