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    PDE6H phosphodiesterase 6H [ Bos taurus (domestic cattle) ]

    Gene ID: 281978, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PDE6Hprovided by VGNC
    Official Full Name
    phosphodiesterase 6Hprovided by VGNC
    Primary source
    VGNC:VGNC:32684
    See related
    BGD:BT15387; Ensembl:ENSBTAG00000013635
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PDE6H in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (94924016..94933948, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene RAS like estrogen regulated growth inhibitor Neighboring gene uncharacterized LOC112446622 Neighboring gene Rho GDP dissociation inhibitor beta Neighboring gene endoplasmic reticulum protein 27

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phosphodiesterase inhibitor specific to a subset of bovine retinal cones. Hamilton SE, et al. J Biol Chem, 1990 Jul 5. PMID 2162841
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cGMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of epidermal growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in visual perception IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in photoreceptor outer segment membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
    Names
    GMP-PDE gamma
    phosphodiesterase 6H, cGMP-specific, cone, gamma
    NP_776847.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174422.2 → NP_776847.1  retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

      See identical proteins and their annotated locations for NP_776847.1

      Status: PROVISIONAL

      Source sequence(s)
      J05578
      UniProtKB/Swiss-Prot
      P22571
      Related
      ENSBTAP00000018123.2, ENSBTAT00000018123.4
      Conserved Domains (1) summary
      pfam04868
      Location:2 → 83
      PDE6_gamma; Retinal cGMP phosphodiesterase, gamma subunit

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      94924016..94933948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22571.1 GenPept UniProtKB/Swiss-Prot:P22571

    Gene LinkOut

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    Research Materials