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    klhl11 kelch-like family member 11 [ Danio rerio (zebrafish) ]

    Gene ID: 327313, updated on 2-Nov-2024

    Summary

    Official Symbol
    klhl11provided by ZNC
    Official Full Name
    kelch-like family member 11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5524
    See related
    Ensembl:ENSDARG00000045130 AllianceGenome:ZFIN:ZDB-GENE-030131-5524
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56044; wu:fd21e01
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KLHL11 (kelch like family member 11). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See klhl11 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (13959260..13966184, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (13922965..13927881, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496799 Neighboring gene DBF4B-CDC7 kinase regulatory subunit Neighboring gene FKBP prolyl isomerase 10b Neighboring gene ATP citrate lyase b Neighboring gene si:ch211-217a12.1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    kelch-like protein 11
    Names
    kelch-like 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199783.2NP_956077.2  kelch-like protein 11

      Status: VALIDATED

      Source sequence(s)
      CR847824
      Related
      ENSDARP00000066367.3, ENSDART00000066368.4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      13959260..13966184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)