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    Jhy junctional cadherin complex regulator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315578, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Jhyprovided by RGD
    Official Full Name
    junctional cadherin complex regulatorprovided by RGD
    Primary source
    RGD:1309108
    See related
    EnsemblRapid:ENSRNOG00000008138 AllianceGenome:RGD:1309108
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309108
    Summary
    Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; cilium assembly; and regulation of establishment of planar polarity. Predicted to be located in extracellular region. Orthologous to human JHY (junctional cadherin complex regulator). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 38.8), Brain (RPKM 12.2) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Jhy in Genome Data Viewer
    Location:
    8q22
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (50173602..50230429, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (41276501..41333383, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (45084067..45140570, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 2, pseudogene 1 Neighboring gene brain specific homeobox Neighboring gene uncharacterized LOC134480158 Neighboring gene uncharacterized LOC134480157 Neighboring gene cytotoxic and regulatory T cell molecule Neighboring gene ubiquitin associated and SH3 domain containing, B Neighboring gene uncharacterized LOC134480159

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within axoneme assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within brain development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within cerebrospinal fluid circulation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within establishment of localization in cell ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of establishment of planar polarity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    jhy protein homolog; junctional cadherin complex regulator
    Names
    juvenile hydrocephalus
    uncharacterized protein C11orf63 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001429449.1 → NP_001416378.1  junctional cadherin complex regulator isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    2. NM_001429450.1 → NP_001416379.1  junctional cadherin complex regulator isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      F1LZA7

    3. NM_001429451.1 → NP_001416380.1  junctional cadherin complex regulator isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      F1LZA7

    4. NM_001429452.1 → NP_001416381.1  junctional cadherin complex regulator isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      F1LZA7

    5. NM_001429453.1 → NP_001416382.1  junctional cadherin complex regulator isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      50173602..50230429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082325.2 → XP_038938253.1  jhy protein homolog isoform X1

      Related
      ENSRNOP00000010743.9, ENSRNOT00000010743.9
      Conserved Domains (1) summary
      pfam15261
      Location:654 → 773
      DUF4591; Domain of unknown function (DUF4591)

    2. XM_039082327.2 → XP_038938255.1  jhy protein homolog isoform X2

      Conserved Domains (1) summary
      pfam15261
      Location:650 → 769
      DUF4591; Domain of unknown function (DUF4591)

    3. XM_039082328.2 → XP_038938256.1  jhy protein homolog isoform X2

      Conserved Domains (1) summary
      pfam15261
      Location:650 → 769
      DUF4591; Domain of unknown function (DUF4591)

    4. XM_039082326.2 → XP_038938254.1  jhy protein homolog isoform X2

      Related
      ENSRNOP00000106527.1, ENSRNOT00000131570.1
      Conserved Domains (1) summary
      pfam15261
      Location:650 → 769
      DUF4591; Domain of unknown function (DUF4591)

    5. XM_039082329.2 → XP_038938257.1  jhy protein homolog isoform X3

      Conserved Domains (1) summary
      pfam15261
      Location:491 → 610
      DUF4591; Domain of unknown function (DUF4591)
    Nucleotide Protein Strain
    Heading Accession and Version

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