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    Psme3ip1 proteasome activator subunit 3 interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307652, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Psme3ip1provided by RGD
    Official Full Name
    proteasome activator subunit 3 interacting protein 1provided by RGD
    Primary source
    RGD:1307433
    See related
    EnsemblRapid:ENSRNOG00000017841 AllianceGenome:RGD:1307433
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Nip30; Fam192a; RGD1307433
    Summary
    Predicted to be involved in negative regulation of proteasomal protein catabolic process and negative regulation of protein binding activity. Predicted to be active in nucleus. Orthologous to human PSME3IP1 (proteasome activator subunit 3 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 133.9), Thymus (RPKM 113.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    19p13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (10407382..10436029)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (10401400..10430059)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10827057..10856747)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene plasmolipin Neighboring gene ADP-ribosylation factor like GTPase 2 binding protein Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene small nucleolar RNA SNORA5 Neighboring gene uncharacterized LOC134483687 Neighboring gene copine 2 Neighboring gene uncharacterized LOC134483689

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ. Jonik-Nowak B, et al. Proc Natl Acad Sci U S A, 2018 Jul 10. PMID 29934401, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of proteasomal protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    PSME3-interacting protein
    Names
    NEFA-interacting nuclear protein NIP30
    family with sequence similarity 192, member A
    protein FAM192A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014014.1 → NP_001014036.1  PSME3-interacting protein

      See identical proteins and their annotated locations for NP_001014036.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079145
      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Related
      ENSRNOP00000024120.6, ENSRNOT00000024120.7
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      10407382..10436029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097714.2 → XP_038953642.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    2. XM_063277993.1 → XP_063134063.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90

    3. XM_039097712.2 → XP_038953640.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    4. XM_063277992.1 → XP_063134062.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90

    5. XM_063277991.1 → XP_063134061.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Related
      ENSRNOP00000103465.1, ENSRNOT00000128462.1

    6. XM_006255110.4 → XP_006255172.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006255172.1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    7. XM_063277994.1 → XP_063134064.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90

    8. XM_039097711.2 → XP_038953639.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    9. XM_006255111.3 → XP_006255173.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006255173.1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    10. XM_017601276.3 → XP_017456765.1  PSME3-interacting protein isoform X1

      UniProtKB/TrEMBL
      F7EUG6, Q6AY90
      Conserved Domains (1) summary
      pfam10187
      Location:15 → 98
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    Nucleotide Protein Strain
    Heading Accession and Version

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