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    Sanbr SANT and BTB domain regulator of CSR [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305579, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Sanbrprovided by RGD
    Official Full Name
    SANT and BTB domain regulator of CSRprovided by RGD
    Primary source
    RGD:1305110
    See related
    EnsemblRapid:ENSRNOG00000054669 AllianceGenome:RGD:1305110
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305110
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in isotype switching. Orthologous to human SANBR (SANT and BTB domain regulator of CSR). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 130.9), Lung (RPKM 84.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sanbr in Genome Data Viewer
    Location:
    14q22
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (101717619..101787092, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (97516652..97585955, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (108305343..108376618, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 34 Neighboring gene uncharacterized LOC108352815 Neighboring gene similar to human chromosome 2 open reading frame 74 Neighboring gene activator of HSP90 ATPase homolog 2 Neighboring gene deoxycytidine kinase, pseudogene 1 Neighboring gene peroxisomal biogenesis factor 13 Neighboring gene pseudouridine synthase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in isotype switching IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in isotype switching ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in isotype switching ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    SANT and BTB domain regulator of class switch recombination

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100971.1 → NP_001094441.1  SANT and BTB domain regulator of class switch recombination isoform 1

      See identical proteins and their annotated locations for NP_001094441.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128776
      UniProtKB/Swiss-Prot
      A1A5R8
      UniProtKB/TrEMBL
      A0A0G2K7U6
      Conserved Domains (1) summary
      pfam11822
      Location:147 → 449
      DUF3342; Domain of unknown function (DUF3342)

    2. NM_001414964.1 → NP_001401893.1  SANT and BTB domain regulator of class switch recombination isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8L2R4S9, A6JQ75
      Related
      ENSRNOP00000071734.2, ENSRNOT00000088116.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      101717619..101787092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273270.1 → XP_063129340.1  SANT and BTB domain regulator of class switch recombination isoform X5

    2. XM_063273269.1 → XP_063129339.1  SANT and BTB domain regulator of class switch recombination isoform X2

      UniProtKB/Swiss-Prot
      A1A5R8
      Related
      ENSRNOP00000074352.2, ENSRNOT00000085886.3

    3. XM_039092096.2 → XP_038948024.1  SANT and BTB domain regulator of class switch recombination isoform X3

      UniProtKB/TrEMBL
      A0A0G2K7U6
      Conserved Domains (1) summary
      pfam11822
      Location:113 → 137
      DUF3342; Domain of unknown function (DUF3342)

    4. XM_017599249.3 → XP_017454738.1  SANT and BTB domain regulator of class switch recombination isoform X1

      UniProtKB/TrEMBL
      A0A0G2K7U6
      Conserved Domains (1) summary
      pfam11822
      Location:147 → 248
      DUF3342; Domain of unknown function (DUF3342)

    5. XM_039092091.2 → XP_038948019.1  SANT and BTB domain regulator of class switch recombination isoform X1

      UniProtKB/TrEMBL
      A0A0G2K7U6
      Conserved Domains (1) summary
      pfam11822
      Location:147 → 248
      DUF3342; Domain of unknown function (DUF3342)

    6. XM_063273268.1 → XP_063129338.1  SANT and BTB domain regulator of class switch recombination isoform X1

    7. XM_039092097.2 → XP_038948025.1  SANT and BTB domain regulator of class switch recombination isoform X6

    8. XM_017599251.3 → XP_017454740.1  SANT and BTB domain regulator of class switch recombination isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1A5R8.1 GenPept UniProtKB/Swiss-Prot:A1A5R8

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