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    BCL11A BCL11 transcription factor A [ Bos taurus (domestic cattle) ]

    Gene ID: 538680, updated on 10-Oct-2024

    Summary

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    Official Symbol
    BCL11Aprovided by VGNC
    Official Full Name
    BCL11 transcription factor Aprovided by VGNC
    Primary source
    VGNC:VGNC:59205
    See related
    BGD:BT18112; Ensembl:ENSBTAG00000016534
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See BCL11A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (43208356..43309895, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tyrosine (anticodon AUA) Neighboring gene bublin coiled-coil protein-like Neighboring gene uncharacterized LOC104973361 Neighboring gene endogenous retrovirus group K member 7 Gag polyprotein-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139389

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of dendrite development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    B-cell lymphoma/leukemia 11A
    Names
    B cell CLL/lymphoma 11A
    B-cell CLL/lymphoma 11A (zinc finger protein)
    BAF chromatin remodeling complex subunit BCL11A
    BCL11A, BAF complex component

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076121.2 → NP_001069589.1  B-cell lymphoma/leukemia 11A

      See identical proteins and their annotated locations for NP_001069589.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000011
      UniProtKB/TrEMBL
      Q17QR0

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43208356..43309895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891379.1 → XP_059747362.1  B-cell lymphoma/leukemia 11A isoform X12

    2. XM_059891376.1 → XP_059747359.1  B-cell lymphoma/leukemia 11A isoform X8

      UniProtKB/TrEMBL
      A0AAA9SVF6
      Related
      ENSBTAP00000088172.1, ENSBTAT00000132757.1

    3. XM_059891382.1 → XP_059747365.1  B-cell lymphoma/leukemia 11A isoform X14

    4. XM_010809966.4 → XP_010808268.1  B-cell lymphoma/leukemia 11A isoform X7

      See identical proteins and their annotated locations for XP_010808268.1

      UniProtKB/TrEMBL
      A0A3Q1LXF2, A0A3Q1MLZ2
      Related
      ENSBTAP00000072743.2, ENSBTAT00000069124.2
      Conserved Domains (3) summary
      sd00017
      Location:379 → 399
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:378 → 399
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:391 → 416
      zf-H2C2_2; Zinc-finger double domain

    5. XM_059891381.1 → XP_059747364.1  B-cell lymphoma/leukemia 11A isoform X13

    6. XM_059891375.1 → XP_059747358.1  B-cell lymphoma/leukemia 11A isoform X5

    7. XM_010809967.3 → XP_010808269.2  B-cell lymphoma/leukemia 11A isoform X3

    8. XM_059891378.1 → XP_059747361.1  B-cell lymphoma/leukemia 11A isoform X11

    9. XM_059891377.1 → XP_059747360.1  B-cell lymphoma/leukemia 11A isoform X10

      UniProtKB/TrEMBL
      A0A3Q1N018
      Related
      ENSBTAP00000061912.2, ENSBTAT00000069722.2

    10. XM_015473446.3 → XP_015328932.1  B-cell lymphoma/leukemia 11A isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LXF2
      Conserved Domains (3) summary
      sd00017
      Location:710 → 730
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:709 → 730
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:357 → 382
      zf-H2C2_2; Zinc-finger double domain

    11. XM_015473445.3 → XP_015328931.1  B-cell lymphoma/leukemia 11A isoform X4

      UniProtKB/TrEMBL
      A0A0A8JC39, A0A3Q1LXF2
      Related
      ENSBTAP00000060200.2, ENSBTAT00000073984.2
      Conserved Domains (3) summary
      sd00017
      Location:744 → 764
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:743 → 764
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:391 → 416
      zf-H2C2_2; Zinc-finger double domain

    12. XM_015473444.3 → XP_015328930.2  B-cell lymphoma/leukemia 11A isoform X2

    13. XM_024998951.2 → XP_024854719.2  B-cell lymphoma/leukemia 11A isoform X1

    14. XM_024998955.2 → XP_024854723.1  B-cell lymphoma/leukemia 11A isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LXF2
      Conserved Domains (3) summary
      sd00017
      Location:592 → 612
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:591 → 612
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:239 → 264
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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