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    PI4KA phosphatidylinositol 4-kinase alpha [ Pan paniscus (pygmy chimpanzee) ]

    Gene ID: 100980877, updated on 10-Oct-2024

    Summary

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    Gene symbol
    PI4KA
    Gene description
    phosphatidylinositol 4-kinase alpha
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan paniscus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See PI4KA in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    56
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 23 NC_085927.1 (30414241..30565263, complement)
    RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 22 NC_073271.1 (32963144..33114773, complement)

    Chromosome 23 - NC_085927.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 191B-like Neighboring gene uncharacterized LOC134730112 Neighboring gene transmembrane protein 191A Neighboring gene serpin family D member 1 Neighboring gene synaptosome associated protein 29 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene small nucleolar RNA U3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol 4-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4-kinase alpha
    Names
    putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Genomic

    1. NC_085927.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

      Range
      30414241..30565263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034948745.4 → XP_034804636.2  phosphatidylinositol 4-kinase alpha isoform X4

    2. XM_034948743.4 → XP_034804634.2  phosphatidylinositol 4-kinase alpha isoform X2

    3. XM_034948744.3 → XP_034804635.1  phosphatidylinositol 4-kinase alpha isoform X3

      UniProtKB/TrEMBL
      A0A2R9B713
      Conserved Domains (2) summary
      cd00871
      Location:1538 → 1713
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1774 → 2092
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    4. XM_034948740.3 → XP_034804631.1  phosphatidylinositol 4-kinase alpha isoform X1

      UniProtKB/TrEMBL
      A0A2R9B713
      Conserved Domains (2) summary
      cd00871
      Location:1560 → 1735
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1796 → 2114
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

    5. XM_063603229.1 → XP_063459299.1  phosphatidylinositol 4-kinase alpha isoform X6

    6. XM_034948746.3 → XP_034804637.1  phosphatidylinositol 4-kinase alpha isoform X5

      UniProtKB/TrEMBL
      A0A2R9B713
      Conserved Domains (2) summary
      cd00871
      Location:1506 → 1681
      PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
      cd05167
      Location:1742 → 2060
      PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha
    Nucleotide Protein
    Heading Accession and Version

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