U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    KMT2E lysine methyltransferase 2E (inactive) [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100173903, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    KMT2E
    Gene description
    lysine methyltransferase 2E (inactive)
    Locus tag
    CR201_G0018070
    See related
    Ensembl:ENSPPYG00000017888
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Also known as
    MLL5
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KMT2E in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 6 NC_071991.2 (101721205..101823889)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 7 NC_071992.1 (95543770..95646445)

    Chromosome 6 - NC_071991.2Genomic Context describing neighboring genes Neighboring gene origin recognition complex subunit 5 Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene uncharacterized LOC103891186 Neighboring gene SRSF protein kinase 2 Neighboring gene large ribosomal subunit protein eL36-like Neighboring gene RWD domain-containing protein 4-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • DKFZp459J0914

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rpd3L-Expanded complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of Set3 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    inactive histone-lysine N-methyltransferase 2E
    Names
    myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071991.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      101721205..101823889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002818325.6 → XP_002818371.3  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53
      Related
      ENSPPYP00000020053.3
      Conserved Domains (7) summary
      smart00317
      Location:343 → 452
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd15550
      Location:120 → 163
      PHD_MLL5; PHD finger found in mixed lineage leukemia 5 (MLL5)
      pfam03326
      Location:1288 → 1524
      Herpes_TAF50; Herpesvirus transcription activation factor (transactivator)
      pfam09606
      Location:1463 → 1828
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl25549
      Location:550 → 605
      ARGLU; Arginine and glutamate-rich 1
      cl25742
      Location:561 → 669
      ERM; Ezrin/radixin/moesin family
      cl26464
      Location:1740 → 1845
      Atrophin-1; Atrophin-1 family

    2. XM_054560595.2 → XP_054416570.1  inactive histone-lysine N-methyltransferase 2E isoform X2

    3. XM_054560591.2 → XP_054416566.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    4. XM_054560593.2 → XP_054416568.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    5. XM_054560594.2 → XP_054416569.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    6. XM_054560589.2 → XP_054416564.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    7. XM_054560590.2 → XP_054416565.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    8. XM_024250259.3 → XP_024106027.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53
      Conserved Domains (7) summary
      smart00317
      Location:343 → 452
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cd15550
      Location:120 → 163
      PHD_MLL5; PHD finger found in mixed lineage leukemia 5 (MLL5)
      pfam03326
      Location:1288 → 1524
      Herpes_TAF50; Herpesvirus transcription activation factor (transactivator)
      pfam09606
      Location:1463 → 1828
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl25549
      Location:550 → 605
      ARGLU; Arginine and glutamate-rich 1
      cl25742
      Location:561 → 669
      ERM; Ezrin/radixin/moesin family
      cl26464
      Location:1740 → 1845
      Atrophin-1; Atrophin-1 family

    9. XM_063725761.1 → XP_063581831.1  inactive histone-lysine N-methyltransferase 2E isoform X1

      UniProtKB/TrEMBL
      A0A2J8VL06, H2PN53

    10. XM_054560597.1 → XP_054416572.1  inactive histone-lysine N-methyltransferase 2E isoform X3

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials