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    MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100442572, updated on 6-Jun-2024

    Summary

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    Gene symbol
    MAP4K2
    Gene description
    mitogen-activated protein kinase kinase kinase kinase 2
    Locus tag
    CR201_G0031347
    See related
    Ensembl:ENSPPYG00000003096
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 9
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 9 NC_071994.2 (9893020..9906722)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 11 NC_071996.1 (9870694..9884350)

    Chromosome 9 - NC_071994.2Genomic Context describing neighboring genes Neighboring gene CDC42 binding protein kinase gamma Neighboring gene menin 1 Neighboring gene uncharacterized LOC129048896 Neighboring gene splicing factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071994.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      9893020..9906722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024255929.3 → XP_024111697.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A2J8TYU0, A0A2J8TYU1, H2NCY9
      Related
      ENSPPYP00000003581.3
      Conserved Domains (2) summary
      smart00036
      Location:488 → 800
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      cd06613
      Location:16 → 272
      STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

    2. XM_054525669.2 → XP_054381644.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X1

    3. XM_063728380.1 → XP_063584450.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X2

    4. XM_063728381.1 → XP_063584451.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X4

      UniProtKB/TrEMBL
      A0A2J8TYT3, A0A2J8TYU0
    Nucleotide Protein
    Heading Accession and Version

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