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    ROCK2 Rho associated coiled-coil containing protein kinase 2 [ Echinops telfairi (small Madagascar hedgehog) ]

    Gene ID: 101646611, updated on 20-Sep-2024

    Summary

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    Gene symbol
    ROCK2
    Gene description
    Rho associated coiled-coil containing protein kinase 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Echinops telfairi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops
    Orthologs
    human mouse all
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    Genomic context

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    See ROCK2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current ASM31398v2 (GCF_000313985.2) Unplaced Scaffold NW_022103906.1 (96150041..96296564)
    101 previous assembly EchTel2.0 (GCF_000313985.1) Unplaced Scaffold NW_004558701.1 (5357071..5501856, complement)

    NW_022103906.1Genomic Context describing neighboring genes Neighboring gene E2F transcription factor 6 Neighboring gene pre-mRNA 3' end processing protein WDR33-like Neighboring gene transcription initiation factor IIA subunit 2-like Neighboring gene U6atac minor spliceosomal RNA Neighboring gene U2 spliceosomal RNA Neighboring gene phosphate carrier protein, mitochondrial-like Neighboring gene solute carrier family 66 member 3 Neighboring gene ciliary microtubule inner protein 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cortical actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of centrosome duplication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho-associated protein kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Echinops telfairi Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM31398v2 Primary Assembly

    Genomic

    1. NW_022103906.1 Reference ASM31398v2 Primary Assembly

      Range
      96150041..96296564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045286617.1 → XP_045142552.1  rho-associated protein kinase 2 isoform X1

    2. XM_045286618.1 → XP_045142553.1  rho-associated protein kinase 2 isoform X4

    3. XM_045286614.1 → XP_045142549.1  rho-associated protein kinase 2 isoform X1

    4. XM_045286616.1 → XP_045142551.1  rho-associated protein kinase 2 isoform X3

    5. XM_045286615.1 → XP_045142550.1  rho-associated protein kinase 2 isoform X2

    Nucleotide Protein
    Heading Accession and Version

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