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    CG4830 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41477, updated on 2-Nov-2024

    Summary

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    Official Symbol
    CG4830provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037996
    Locus tag
    Dmel_CG4830
    See related
    AllianceGenome:FB:FBgn0037996
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4830
    Summary
    Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See CG4830 in Genome Data Viewer
    Location:
    87B2-87B2; 3-52 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12208159..12210360, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8033881..8036082, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Adenosine kinase 1 Neighboring gene transfer RNA:Threonine-TGT 1-1 Neighboring gene uncharacterized protein Neighboring gene Component of oligomeric golgi complex 1 Neighboring gene antisense RNA:CR46012 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Inouye S. Cell Mol Life Sci, 2010 Feb. PMID 19859663, Free PMC Article
    2. Characterization of CG6178 gene product with high sequence similarity to firefly luciferase in Drosophila melanogaster. Oba Y, et al. Gene, 2004 Mar 31. PMID 15033536
    3. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. Oba Y, et al. Biosci Biotechnol Biochem, 2005 Apr. PMID 15849423
    4. Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor. Rand MD, et al. Toxicol Sci, 2008 Jul. PMID 18367466
    5. split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80. Ewen-Campen B, et al. Proc Natl Acad Sci U S A, 2023 Jun 13. PMID 37276389, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables CoA-ligase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables fatty acid ligase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables long-chain fatty acid-CoA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in fatty-acyl-CoA biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in long-chain fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4830-PA
    NP_650160.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12208159..12210360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141903.3 → NP_650160.1  uncharacterized protein Dmel_CG4830 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650160.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGC5
      Related
      FBpp0082094
      Conserved Domains (2) summary
      COG0318
      Location:18 → 529
      CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
      cl17068
      Location:46 → 518
      AFD_class_I; Adenylate forming domain, Class I superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGC5 Q9VGC5

    Gene LinkOut

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