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    APLP2 amyloid beta precursor like protein 2 [ Protopterus annectens (West African lungfish) ]

    Gene ID: 122809517, updated on 22-Mar-2024

    Summary

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    Gene symbol
    APLP2
    Gene description
    amyloid beta precursor like protein 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Protopterus annectens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Dipnomorpha; Ceratodontiformes; Lepidosirenoidei; Protopteridae; Protopterus
    Orthologs
    human mouse all
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    Genomic context

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    See APLP2 in Genome Data Viewer
    Location:
    chromosome: 8.part0
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    100 current PAN1.0 (GCF_019279795.1) 8.part0 NC_056741.1 (1496251517..1497683851, complement)

    Chromosome 8.part0 - NC_056741.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 3A Neighboring gene zinc finger and BTB domain containing 16 Neighboring gene PR/SET domain 10 Neighboring gene nuclear factor related to kappaB binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056741.1 Chromosome 8.part0 Reference PAN1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Salamander-like tail regeneration in the West African lungfish. Verissimo KM, et al. Proc Biol Sci, 2020 Sep 30. PMID 32933441, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amyloid-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Protopterus annectens Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference PAN1.0 Primary Assembly

    Genomic

    1. NC_056741.1 Reference PAN1.0 Primary Assembly

      Range
      1496251517..1497683851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044081082.1 → XP_043937017.1  amyloid-like protein 2 isoform X3

      Conserved Domains (2) summary
      smart00006
      Location:34 → 198
      A4_EXTRA; amyloid A4
      cl11943
      Location:339 → 425
      Activator-TraM; Transcriptional activator TraM

    2. XM_044081081.1 → XP_043937016.1  amyloid-like protein 2 isoform X2

      Conserved Domains (3) summary
      smart00006
      Location:34 → 198
      A4_EXTRA; amyloid A4
      cd00109
      Location:311 → 364
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cl11943
      Location:395 → 481
      Activator-TraM; Transcriptional activator TraM

    3. XM_044081080.1 → XP_043937015.1  amyloid-like protein 2 isoform X1

      Conserved Domains (3) summary
      smart00006
      Location:34 → 198
      A4_EXTRA; amyloid A4
      cd00109
      Location:311 → 364
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
      cl11943
      Location:395 → 481
      Activator-TraM; Transcriptional activator TraM
    Nucleotide Protein
    Heading Accession and Version

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