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    CRKL CRK like proto-oncogene, adaptor protein [ Neogale vison (American mink) ]

    Gene ID: 122903191, updated on 22-Mar-2024

    Summary

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    Gene symbol
    CRKL
    Gene description
    CRK like proto-oncogene, adaptor protein
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Neogale vison
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
    Orthologs
    human mouse all
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    Genomic context

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    See CRKL in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    100 current ASM_NN_V1 (GCF_020171115.1) 3 NC_058093.1 (213020819..213060384, complement)

    Chromosome 3 - NC_058093.1Genomic Context describing neighboring genes Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene AIF family member 3 Neighboring gene synaptosome associated protein 29 Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_058093.1 Chromosome 3 Reference ASM_NN_V1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    crk-like protein
    Names
    Crk-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM_NN_V1 Primary Assembly

    Genomic

    1. NC_058093.1 Reference ASM_NN_V1 Primary Assembly

      Range
      213020819..213060384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044243771.1 → XP_044099706.1  crk-like protein

      UniProtKB/TrEMBL
      A0A8C7BRQ1, U6CS22
      Conserved Domains (3) summary
      cd09926
      Location:6 → 106
      SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
      cd11758
      Location:126 → 180
      SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
      cd11759
      Location:237 → 293
      SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    Nucleotide Protein
    Heading Accession and Version

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