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    gch1 GTP cyclohydrolase 1 [ Plectropomus leopardus (leopard coralgrouper) ]

    Gene ID: 121943123, updated on 22-Mar-2024

    Summary

    Gene symbol
    gch1
    Gene description
    GTP cyclohydrolase 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Plectropomus leopardus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae; Epinephelini; Plectropomus
    Orthologs
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    Genomic context

    See gch1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    100 current YSFRI_Pleo_2.0 (GCF_008729295.1) 1 NC_056463.1 (7269548..7293508)

    Chromosome 1 - NC_056463.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121946397 Neighboring gene uncharacterized LOC121946407 Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene sterile alpha motif domain containing 4A Neighboring gene endoplasmic reticulum oxidoreductase 1 alpha

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_056463.1 Chromosome 1 Reference YSFRI_Pleo_2.0 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables GTP cyclohydrolase I activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in tetrahydrofolate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    LOW QUALITY PROTEIN: GTP cyclohydrolase 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Plectropomus leopardus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference YSFRI_Pleo_2.0 Primary Assembly

    Genomic

    1. NC_056463.1 Reference YSFRI_Pleo_2.0 Primary Assembly

      Range
      7269548..7293508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042486545.1XP_042342479.1  LOW QUALITY PROTEIN: GTP cyclohydrolase 1

      Conserved Domains (1) summary
      cd00642
      Location:71255
      GTP_cyclohydro1; GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria. In ...