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    PLEKHA7 pleckstrin homology domain containing A7 [ Gallus gallus (chicken) ]

    Gene ID: 423069, updated on 10-Oct-2024

    Summary

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    Symbol
    PLEKHA7provided by CGNC
    Full Name
    pleckstrin homology domain containing A7provided by CGNC
    Primary source
    CGNC:4568
    See related
    Ensembl:ENSGALG00010023181
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PLEKHA7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (11190036..11330627, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (11159271..11299971, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene SRY-box 6 Neighboring gene uncharacterized LOC107053389 Neighboring gene C11orf58 homolog Neighboring gene uncharacterized LOC121110974 Neighboring gene uncharacterized LOC112532499 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Neighboring gene ribosomal protein S13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion mediated by cadherin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in epithelial cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pore complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zonula adherens maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of pore complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in zonula adherens IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pleckstrin homology domain-containing family A member 7
    Names
    pleckstrin homology domain containing, family A member 2
    pleckstrin homology domain containing, family A member 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11190036..11330627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701359.2 → XP_040557293.1  pleckstrin homology domain-containing family A member 7 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Related
      ENSGALP00010034260.1, ENSGALT00010056518.1
      Conserved Domains (5) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      PHA03247
      Location:914 → 1093
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:731 → 844
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    2. XM_046942008.1 → XP_046797964.1  pleckstrin homology domain-containing family A member 7 isoform X11

    3. XM_015286637.4 → XP_015142123.1  pleckstrin homology domain-containing family A member 7 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZRV1
      Conserved Domains (4) summary
      cd13248
      Location:130 → 253
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:136 → 252
      PH; PH domain
      pfam00397
      Location:10 → 39
      WW; WW domain
      cl12013
      Location:707 → 814
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_040701358.2 → XP_040557292.1  pleckstrin homology domain-containing family A member 7 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (5) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      PHA03247
      Location:894 → 1073
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:711 → 824
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 261
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    5. XM_015286636.4 → XP_015142122.1  pleckstrin homology domain-containing family A member 7 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZTU5, A0A8V0ZTV0
      Related
      ENSGALP00010034254.1, ENSGALT00010056512.1
      Conserved Domains (4) summary
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:164 → 280
      PH; PH domain
      pfam00397
      Location:55 → 84
      WW; WW domain
      pfam04514
      Location:617 → 772
      BTV_NS2; Bluetongue virus non-structural protein NS2

    6. XM_015286632.4 → XP_015142118.1  pleckstrin homology domain-containing family A member 7 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (4) summary
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:164 → 280
      PH; PH domain
      pfam00397
      Location:55 → 84
      WW; WW domain
      cl12013
      Location:735 → 842
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    7. XM_046942005.1 → XP_046797961.1  pleckstrin homology domain-containing family A member 7 isoform X10

    8. XM_046942004.1 → XP_046797960.1  pleckstrin homology domain-containing family A member 7 isoform X10

    9. XM_015286639.4 → XP_015142125.1  pleckstrin homology domain-containing family A member 7 isoform X10

      UniProtKB/TrEMBL
      A0A1D5PWH3
      Related
      ENSGALP00010034250.1, ENSGALT00010056507.1
      Conserved Domains (3) summary
      cd13248
      Location:53 → 176
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      cl25732
      Location:626 → 739
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26464
      Location:809 → 988
      Atrophin-1; Atrophin-1 family

    10. XM_046942007.1 → XP_046797963.1  pleckstrin homology domain-containing family A member 7 isoform X10

    11. XM_040701363.2 → XP_040557297.1  pleckstrin homology domain-containing family A member 7 isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:834 → 1013
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:651 → 764
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:98 → 201
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    12. XM_046942003.1 → XP_046797959.1  pleckstrin homology domain-containing family A member 7 isoform X10

    13. XM_040701362.2 → XP_040557296.1  pleckstrin homology domain-containing family A member 7 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:837 → 1016
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:654 → 767
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:81 → 204
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    14. XM_040701361.1 → XP_040557295.1  pleckstrin homology domain-containing family A member 7 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (2) summary
      COG0419
      Location:662 → 775
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:109 → 212
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    15. XM_015286638.3 → XP_015142124.3  pleckstrin homology domain-containing family A member 7 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:865 → 1044
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:682 → 795
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:109 → 232
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    16. XM_046942006.1 → XP_046797962.1  pleckstrin homology domain-containing family A member 7 isoform X10

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      11159271..11299971 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040673414.2 → XP_040529348.1  pleckstrin homology domain-containing family A member 7 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (5) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      PHA03247
      Location:914 → 1093
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:731 → 844
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    2. XM_046919497.1 → XP_046775453.1  pleckstrin homology domain-containing family A member 7 isoform X11

    3. XM_040673416.2 → XP_040529350.1  pleckstrin homology domain-containing family A member 7 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZRV1
      Conserved Domains (4) summary
      PHA03247
      Location:886 → 1065
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:703 → 816
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:130 → 253
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    4. XM_040673413.2 → XP_040529347.1  pleckstrin homology domain-containing family A member 7 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (5) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      PHA03247
      Location:894 → 1073
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:711 → 824
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 261
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    5. XM_040673415.2 → XP_040529349.1  pleckstrin homology domain-containing family A member 7 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (4) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      COG0419
      Location:662 → 817
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    6. XM_040673412.2 → XP_040529346.1  pleckstrin homology domain-containing family A member 7 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZTV0
      Conserved Domains (5) summary
      smart00456
      Location:54 → 85
      WW; Domain with 2 conserved Trp (W) residues
      PHA03247
      Location:914 → 1093
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:731 → 844
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd00201
      Location:12 → 40
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd13248
      Location:158 → 281
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    7. XM_046919494.1 → XP_046775450.1  pleckstrin homology domain-containing family A member 7 isoform X10

    8. XM_046919493.1 → XP_046775449.1  pleckstrin homology domain-containing family A member 7 isoform X10

    9. XM_040673422.2 → XP_040529356.1  pleckstrin homology domain-containing family A member 7 isoform X10

      UniProtKB/TrEMBL
      A0A1D5PWH3
      Conserved Domains (3) summary
      PHA03247
      Location:809 → 988
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:626 → 739
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:53 → 176
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    10. XM_046919496.1 → XP_046775452.1  pleckstrin homology domain-containing family A member 7 isoform X10

    11. XM_040673421.2 → XP_040529355.1  pleckstrin homology domain-containing family A member 7 isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:834 → 1013
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:651 → 764
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:98 → 201
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    12. XM_046919492.1 → XP_046775448.1  pleckstrin homology domain-containing family A member 7 isoform X10

    13. XM_040673420.2 → XP_040529354.1  pleckstrin homology domain-containing family A member 7 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:837 → 1016
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:654 → 767
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:81 → 204
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    14. XM_040673419.1 → XP_040529353.1  pleckstrin homology domain-containing family A member 7 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:845 → 1024
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:662 → 775
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:109 → 212
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    15. XM_040673417.1 → XP_040529351.1  pleckstrin homology domain-containing family A member 7 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZRT7
      Conserved Domains (3) summary
      PHA03247
      Location:865 → 1044
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:682 → 795
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd13248
      Location:109 → 232
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    16. XM_046919495.1 → XP_046775451.1  pleckstrin homology domain-containing family A member 7 isoform X10

    Nucleotide Protein Strain
    Heading Accession and Version

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